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Nel marzo del 1991 il collezionista ed editore Francesco Conz, in collaborazione con il museo MSU di Zagabria, invita per una residenza dʼartista al castello di Brunnenburg di Merano alcuni artisti che avevano fatto parte di Gorgona, avanguardia croata attiva come gruppo tra il 1959 e il 1966. I cinque artisti realizzano tredici opere durante la residenza, tutte su carta dello stesso formato e di ciascuna vengono realizzate quindici copie. Queste avrebbero dovuto far parte di unʼedizione, pensata come un box, che avrebbe dovuto contenere inizialmente anche una riedizione di grande formato di sette vecchi lavori del gruppo, stampata su tela a Como - più un ottavo lavoro ottenuto dalle stesse affiancate in una striscia continua a realizzare una sorta di “opera collettiva -, delle fotografie e un video documentario. il box non sarà mai realizzato prima della morte dello stesso Conz nel 2010, sebbene tutte le sue componenti fossero state prodotte, ad esclusione della cartella che avrebbe dovuto contenerle. I lavori degli artisti sono rimasti allʼinterno dellʼarchivio F. Conz. I due lavori realizzati da Đuro Seder non sembrano riprendere la sua produzione allʼinterno dei gruppo Gorgona, come affermato dallo stesso artista nellʼintervista pubblicata sul dossier monografico della rivista Ricerche di S/Confine. Qui propone infatti un disegno in cui ritorna il suo caratteristico uso di forme irregolari e linee semicircolari, a cui però aggiunge lʼelemento grafico con la reiterazione della scritta “peace” e un secondo disegno derivato da un suo precedente dipinto in cui due profili si fondono in un unico volto. Seder stesso ricorda come nel periodo della residenza, immediatamente precedente allo scoppio della guerra in Croazia, ci fosse «nellʼaria un sentore di intolleranza» e come lʼopera volesse quindi parlare «dell'importanza dell'unità fra le persone».In March 1991 the collector and publisher Francesco Conz, in collaboration with the Muzej Suvremene Umjetnosti - MSU Zagreb, invited a few artists who had been part of Gorgona, the Croatian avant-garde group active between 1959 and 1966, to an artistic residency at the castle of Brunnenburg in Merano, Italy. During their residency, the five artists created thirteen works of art as well as fifteen hand-made copies of each work. All of which were created on the same size of paper. These works should have been part of a box, an art edition that initially should have included large-scale reproductions of seven of the group's old works, printed on canvas in Como, in addition to en eight obtained by merging the former in a continuous strip to create sort of a "collective work" - together with photographs documenting the residency, historical photographs and video interviews filmed in Brunnenburg. Conz died in 2010 but the box was never finished, although all of its components had been created, except for the folder that was supposed to contain them. The works of the artists have since remained in F. Conz's Archive. The two works created by Đuro Seder do not seem to resemble the production of his Gorgona years, as stated by the artist himself in an interview published in the monographic dossier of the magazine Ricerche di S/Confine. In fact, he proposes a drawing with his characteristic use of irregular shapes and semicircular lines, to which he adds a graphic element with the repetition of the word "peace". The second drawing is derived from a previous painting in which two profiles are merging into a single face. Seder himself remembers how during his residency, which immediately preceeded the war in Croatia, there was "a hint of intolerance in the air" and how the work was meant to hilight "the importance of unity among people"

Temperature Dependence on Enzymatic Activity of A82F F87A Mutant and Wild-type Cytochrome P450 BM-3

Cytochrome P450 is an enzyme mainly found in liver cells. It plays a key role in the breakdown of drugs and toxins by hydroxylating substrates making the substrates more water soluble. P450s are also involved in cholesterol and hormone synthesis. The third P450 from bacterium Bacillus Megaterium (BM3) is used as a model P450 enzyme due to its structural similarity to human P450s and due to its efficiency in the hydroxylation of fatty acids. Within the enzyme’s active site, substrates can occupy a distal or proximal conformation monitored by UV-vis spectroscopy. The proximal conformation is more effective when it comes to hydroxylation so a double mutant (A82F/F87A) was developed and it was hypothesized that the mutation would allow for the proximal conformation to be more prevalent and increase the catalytic efficiency. Enzymatic Studies with palmitic (C16:0), eicosanoic (C20:0), and arachidonic (C20:4) acids as substrates were performed for the wild-type and mutant enzyme. Michaelis–Menten Kinetics were used to determine Km, kcat, and catalytic efficiency of the enzymes. The results of the experiments have not supported the hypothesis and the wild-type enzyme has shown to be a more efficient enzyme than the mutant. However, an overall increase in the catalytic efficiency of both mutant and wild type was noted with increasing temperature. Future studies include further experimentation with different chain length and saturation levels of fatty acids as well as looking at the products of enzymatic reactions as a function of temperature by LC/M

Increased Levels of Oxidative Stress in Human Fibroblast Lung Cell Cultures and the Loss of Mitochonndrial Function Due to Exposure to Particulate Matter from September 11, 2001

Not only did over 2,753 individuals perish on the morning of September 11, 2001, many have suffered from mental and physical illnesses ever since. Thousands of individuals experienced breathing complications, asthma and lung cancer. Clinical trials on cancer, including a patient who was exposed to the World Trade Center (WTC) dust, have seen a decrease in the progression of tumor growth with the use of oral nicotinamide adenine dinucleotide (NADH). NADH is naturally occurring within a cell’s mitochondria and aids in the production of adenosine triphosphate (ATP), the energy of the cell. NADH is an anti-aging, energy enhancing substance that also reduces fatigue and successfully treats degenerative medical conditions. NADH is becoming a possible treatment for tumor regression but it is still unknown, on a cellular level, the exact reason why NADH reacts with these cells to prevent further tumor growth. In this study, the amount of NADH produced by normal MRC-5 lung fibroblast cells will be compared to lung cells exposed to WTC dust, using a PROMEGA NAD+/NADH-Glo assay. The same cells will be evaluated to note the decline in the levels of Glutathione to determine the amount Reactive Oxidative Species (ROS) brought onto lung cells by WTC dust. ROS is known to decrease GSH levels by causing oxidative stress that leads to apoptosis. It is important for the cells to maintain high levels of reduced glutathione (GSH) and low levels of oxidized glutathione (GSSG). PROMEGA GSH Glo Glutathione assay will be used to determine if the toxic, mutagenic and apoptotic effects of WTC dust can be shown to be the result of oxidative stress. Lung fibroblast cells will be exposed to various concentrations of WTC dust, ranging from 25-250 parts per million (ppm). It is hypothesized that the cells with the highest concentrations of this toxic particulate matter will experience the most accumulation of oxidative stress, resulting in more NADH being oxidized to NAD+ within the mitochondria, and simultaneous decrease in protective antioxidants as shown in changes in the levels of reduced GSH. This should allow correlations to be made on a more precise cellular mechanism between exposure to this WTC dust, oxidative stress and loss of mitochondrial function seen in the diseases of the exposed first responder population

El cine de propaganda como fenómeno totalitario, el caso de Leni Riefenstahl

Onzenes Jornades de Foment de la Investigació de la FCHS (Any 2005-2006

Patients' attitudes towards and use of the social worker during the early phase of hospitalization for mental illness

Thesis (M.S.)--Boston UniversityBroadly, the purpose of this study is to examiner some aspects of the relationship between the practice of social casework and the treatment of mental illness in the mental hospital setting. It has long been acknowledged that the sociaal worker has a recognized role in the treatment of the mentally ill, since mental illness reflects some failure in social as well as personal adaptation. Social work in mental hospital settings, however, has expanded the concept of its role and undergone modifications. This evolution has been the result of new knowledge and new experiences. "The truth is that casework concepts are dynamic--they change, grow and develop..." This statement apolies as well to casework oriented to a specific setting as to the generic casework processes

Examining Clandestine Social Networks for the Presence of Non-Random Structure

This thesis develops a tractable, statistically sound hypothesis testing framework for the detection, characterization, and estimation of non-random structure in clandestine social networks. Network structure is studied via an observed adjacency matrix, which is assumed to be subject to sampling variability. The vertex set of the network is partitioned into k mutually exclusive and collectively exhaustive subsets, based on available exogenous nodal attribute information. The proposed hypothesis testing framework is employed to statistically quantify a given partition\u27s relativity in explaining the variability in the observed adjacency matrix relative to what can be explained by chance. As a result, valuable insight into the true structure of the network can be obtained. Those partitions that are found to be statistically significant are then used as a basis for estimating the probability that a relationship tie exists between any two vertices in the complete vertex set of the network. The proposed methodology aids in the reduction of the amount of data required for a given network, focusing analyses on those attributes that are most promising. Ample effort is given to both model demonstration and application, including an example using open-source data, illustrating the potential use for the defense community and others

Secondary school administration: Data processing's untapped market?

Thesis (M.B.A.)--Boston Universit

Henri Temianka Correspondence; (seder)

https://digitalcommons.chapman.edu/temianka_correspondence/2804/thumbnail.jp