165 research outputs found

    The Effect of Professional Partnership on the Development of a Mutual‐help Organization

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    The effects of partnership between Schizophrenics Anonymous (SA, a mutual‐help organization) and the Mental Health Association in Michigan (MHAM, a professionally staffed advocacy organization) on SA's growth and development were explored. Following the initiation of a formal partnership, SA groups were more available throughout the state, more likely to be associated with formal mental health settings, and less likely to have leaders who had been participants in other SA groups. Groups with consumer leaders had significantly greater longevity than groups with professional leaders. Changes in the organizational structure and process of SA were also identified. SA leaders reported that SA moved from a collective to a more bureaucratic structure. As a result, there was greater consistency, administrative capacity, and response capacity. This enhanced capacity came with costs reported by SA leaders. The leadership role of SA members became less defined. SA members expressed concerns about the more hierarchical structure of SA's organization, decreased consumer control, increased professional involvement in SA, and an excessive focus on group development as opposed to group maintenance. Mental Health Association in Michigan staff reported that MHAM was also impacted by the partnership, both with regard to internal functioning and external perception. Implications for effective partnerships between mutual‐help and professional organizations are discussed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116999/1/ajcp9193.pd

    Transcriptional Signatures of Tau and Amyloid Neuropathology

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    Alzheimer's disease (AD) is associated with the intracellular aggregation of hyperphosphorylated tau and the accumulation of ÎČ-amyloid in the neocortex. We use transgenic mice harboring human tau (rTg4510) and amyloid precursor protein (J20) mutations to investigate transcriptional changes associated with the progression of tau and amyloid pathology. rTg4510 mice are characterized by widespread transcriptional differences in the entorhinal cortex with changes paralleling neuropathological burden across multiple brain regions. Differentially expressed transcripts overlap with genes identified in genetic studies of familial and sporadic AD. Systems-level analyses identify discrete co-expression networks associated with the progressive accumulation of tau that are enriched for genes and pathways previously implicated in AD pathology and overlap with co-expression networks identified in human AD cortex. Our data provide further evidence for an immune-response component in the accumulation of tau and reveal molecular pathways associated with the progression of AD neuropathology.This article is freely available via Open Access. Click on the Publisher URL to access it via the publisher's site.WT_/Wellcome Trust/United Kingdom MR/M008924/1/MRC_/Medical Research Council/United Kingdompublished version, accepted version, submitted versio

    Animal Counting Toolkit : a practical guide to small-boat surveys for estimating abundance of coastal marine mammals

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    The authors thank Synchronicity Earth, Marisla Foundation, and the US Marine Mammal Commission for seed funding for this program.Small cetaceans (dolphins and porpoises) face serious anthropogenic threats in coastal habitats. These include bycatch in fisheries; exposure to noise, plastic and chemical pollution; disturbance from boaters; and climate change. Generating reliable abundance estimates is essential to assess sustainability of bycatch in fishing gear or any other form of anthropogenic removals and to design conservation and recovery plans for endangered species. Cetacean abundance estimates are lacking from many coastal waters of many developing countries. Lack of funding and training opportunities makes it difficult to fill in data gaps. Even if international funding were found for surveys in developing countries, building local capacity would be necessary to sustain efforts over time to detect trends and monitor biodiversity loss. Large-scale, shipboard surveys can cost tens of thousands of US dollars each day. We focus on methods to generate preliminary abundance estimates from low-cost, small-boat surveys that embrace a ‘training-while-doing’ approach to fill in data gaps while simultaneously building regional capacity for data collection. Our toolkit offers practical guidance on simple design and field data collection protocols that work with small boats and small budgets, but expect analysis to involve collaboration with a quantitative ecologist or statistician. Our audience includes independent scientists, government conservation agencies, NGOs and indigenous coastal communities, with a primary focus on fisheries bycatch. We apply our Animal Counting Toolkit to a small-boat survey in Canada’s Pacific coastal waters to illustrate the key steps in collecting line transect survey data used to estimate and monitor marine mammal abundance.Publisher PDFPeer reviewe

    The role of community-based Hubs in reef restoration: Collaborative monitoring at Moore Reef

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    The Cairns-Port Douglas region is home to multiple coral rehabilitation and stewardship projects supported by scientists, Traditional Owners, and a range of local stakeholders. The Cairns-Port Douglas Reef Hub has been a platform for collaboration across Traditional Owners, tourism operators, not-for-profits and scientists from the Reef Restoration and Adaptation Program (AIMS and CSIRO) to design and deliver a project at Moore Reef that assesses how new techniques for assisted coral recovery can be applied in rubble habitats. The collaborative project evaluates the viability of newly engineered coral seeding devices developed by AIMS, for deploying coral recruits that were spawned in the National Sea Simulator in December 2022 to sites at Moore Reef close to tourist pontoons. This project provides important data to inform future scaling up of restoration activities and provides a model for active involvement of a range of partners. Through this work, the project builds understanding around key ingredients for best-practice, place-based engagement opportunities for Reef communities and the general public

    Agricultural and food security impacts from the 2010 Russia flash drought

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    The flash drought and its associated heat wave that affected western Russia in the summer of 2010 had significant cascading agricultural and socioeconomic impacts. Drought indicators sensitive to soil moisture and evapotranspiration (ET) showed that the flash drought began in June 2010, then intensified rapidly and expanded to cover much of western Russia. By early July, almost all of the major wheat producing regions of Russia were experiencing extreme water stress to the winter and spring wheat crops. The timing of the onset of the flash drought was particularly devastating as the period of most rapid intensification overlapped with the flowering stage for both the winter and spring wheat crops. As a result, wheat yields in Russia were reduced by over 70 percent in top wheat producing oblasts and total wheat production was reduced by 20 million metric tons (MT) compared to the previous seasons. In fulfillment of its recently adopted Food Security Doctrine, the Russian government banned the export of wheat in early August 2010 to preserve wheat for its own consumption. Further compounding matters on a global scale, the significant reduction in wheat production in Russia coincided with wheat production issues in places like western Australia, which led to a large drop in global wheat stocks. The sharp drop in global wheat stocks coincided with a rapid increase in wheat prices across the globe. The rapid increase in wheat prices, partly resulting from the rapid intensification of drought in Russia, led to increased prices for wheat flour and bread in many countries throughout the world. This ultimately led to an increase in poverty and civil unrest in countries like Mozambique and Egypt with a history of inequality and poverty
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