17 research outputs found
Virantanaz – an epic in Vepsian? About the first attempt at an epic
The paper is a brief account of the events of the past 20 years, which have been essential for the fate of the Veps, and brought the author, who found herself in the very heart of the processes of Vepsian language and culture revival, to the idea of creating the epic. Can one create an epic in the language of a people (Vepsians in our case) whose memory has preserved no epic-style pieces of literature, no large oral literary forms, whose folklore heritage is not so rich, the nation itself is a minority, and its language is already red-listed? Or should one? Writing the work was a chance to retrieve from the people’s memory many facts, real or imaginary events, rituals, customs and legends, melodious idioms and sayings, which might help revitalise the people, its language and culture. The paper demonstrates the folklore and mythological background of the epic, represents and substantiates the key aspects of the style poetics, its folk heritage roots
АМЕРИКАНСЬКИЙ МЮЗИКЛ: ПИТАННЯ СТАНОВЛЕННЯ ТА ЖАНРОУТВОРЕННЯ
Purpose of Article. The aim of the study is to give reasons for the American musical's process of formation as a special variety of show forms, the historical aspect of this form, the definition of genre signs of musical and their features. Methodology. Research methodology consists in applying analytical, functional, comparative and art studying, systematic research methods of the American musical's role in stage art, the study of these show forms origins and their importance in modern theatre. Scentific novelty. The scientific novelty of the research lies in the assertion that the general trend of theatrical forms since the late 80s of the last century gave reasons for increasing of the theatricality role in the socio-cultural reality. Conclusion. As a result of the research it can be concluded the following: firstly, the Broadway musical with its brilliance, imagination, rhythmic tact became a special commodity, recognized and admired throughout the world, although its forms were borrowed from many sources; secondly, since the late 80s of the last century an idea of a fancy, carnival nature of social life and the means of its reproduction became popular among Western theorists; thirdly, "Black crook" paved the way for musical to the American scene, launching tradition of luxury entertainment spectacles with various stage effects and dance numbers; fourthly – the most attention was paid to the creation of bright numbers in the structure of the musical comedy score, they were inserted on the advice of artists and kept a strong impression on the audience. According to this the role of the composer-songwriter was growing; fifthly, at the beginning of the XIX century the USA became a centre of musical comedies instead of the Old World. Broadway turned to the capital of the world show business, and gradually musical was turning into a leading genre; and finally – the question of the current state of the classic American genre of the musical theatre periodically rises for producers and critics. It causes debates, generates various predictions about the continued existence of traditional Broadway show, including pessimistic ones.Целью работы является обоснование процесса становления американского мюзикла как особой разновидности зрелищных форм, исторического аспекта данной формы, определения особенностей жанровых признаков мюзикла. Методология исследования заключается в применении аналитического, функционального, сравнительного, искусство- ведческого, системного методов исследования роли американского мюзикла в сценическом искусстве, истоков зрелищно-развлекательных форм и их значения в современном театральном искусстве. Научная новизна исследования за- ключается в утверждении, что общая тенденция театрализации с конца 80-х годов прошлого века дала основания для роста роли театральности в социокультурной реальности. Выводы. Во-первых, бродвейский мюзикл, с его блеском, фантазией, ритмическим тактом, стал особым товаром, который признали и которым восхищались во всем мире, хотя форма его заимствована из многих источников; во-вторых, с конца 80-х годов прошлого века среди западных теоретиков приобрела популярность идея о маскарадном, карнавальном характере общественной жизни и средств его воспроизве- дения; в-третьих, "Черный плут" проложил путь мюзиклу на американской сцене, положив начало традиции роскошных развлекательных зрелищ с применением различных сценических эффектов и использованием танцевальных номеров; четвертый, именно созданию ярких номеров уделяли главное внимание в структуре партитуры музыкальной комедии, вставляли их по совету исполнителей, поскольку они производили впечатление на зрителей. Соответственно, возраста- ла роль композитора-песенника; в-пятых, в начале XIX века центром создания музыкальных комедий вместо Старого Света становится Америка. Бродвей превращается в столицу мирового шоу-бизнеса, а мюзикл – на ведущий жанр; и последнее, вопрос о современном состоянии классического американского жанра мюзикла периодически возникает перед театральными продюсерами и критиками. Он вызывает дискуссии, порождает различные прогнозы относительно дальнейшего существования традиционного бродвейского шоу, в том числе пессимистичные.Метою роботи є обґрунтування процесу становлення американського мюзиклу як особливого різновиду видовищних форм, історичного аспекту даної форми, визначення особливостей жанрових ознак мюзиклу. Методологія полягає у застосуванні аналітичного, функціонального, порівняльного, мистецтвознавчого, системного методів дослідження ролі американського мюзиклу, витоків видовищно-розважальних форм та їх значення у сучасному театральному мистецтві. Наукова новизна дослідження полягає у ствердженні, що загальна тенденція театралізації з кінця 80-х років минулого століття дала підстави для зростання ролі театральності у соціокультурній реальності. Висновки: По-перше, бродвейський мюзикл, з його блиском, фантазією, ритмічним тактом, став особливим товаром, який визнали і яким захоплювалися у всьому світі, хоча його форма запозичена з багатьох джерел; по-друге, з кінця 80-х років минулого століття серед західних теоретиків набули популярності ідея про маскарадний, карнавальний характер суспільного життя і засоби його відтворення; по-третє, "Чорний шахрай" проклав шлях мюзиклу на американській сцені, започаткувавши традицію розкішних розважальних видовищ із за- стосуванням різних сценічних ефектів та використанням танцювальних номерів; вчетверте, саме створенню яскравих номе- рів приділяли головну увагу в структурі партитури музичної комедії, вставляли їх за порадою виконавців, оскільки вони спра- вляли найбільше враження на глядачів. Відповідно, зростала роль композитора-пісняра; по-п`яте, на початку XIX ст. центром створення музичних комедій замість Старого Світу стає Америка. Бродвей перетворюються на столицю світового шоу- бизнесу, а мюзикл – на провідний жанр; і останнє, питання про сучасний стан класичного американського жанру мюзиклу періодично постає перед театральними продюсерами і критиками. Воно викликає дискусії, породжує різні прогнози щодо подальшого існування традиційного бродвейського шоу, зокрема песимістичні
Assessment of ambient air quality in areas influenced by fuel and energy enterprises to provide environmental safety of the population
The article provides the spatial-dynamic and structural hygienic assessment of influence exerted by fuel and energy enterprises on ambient air quality and potential public health risks in the Russian Federation. An average potential health risk level (Rlav) equaled 5.44∙10-4 per one economic entity operating in the ‘Electrical power, gas and steam supply; air conditioning’ branch in the RF as a whole. In the RF regions, the highest potential health risk level per one economic entity was identified in the Siberian Federal District where it equaled 9.9∙10-4. According to the Register, the exposure level (Mi) established for economic entities operating in the ‘Electrical power, gas and steam supply; air conditioning’ branch and belonging to extremely high and high risk categories varies within the range of 0.0928 – 0.0093 and 0.00921 – 0.00092 million people accordingly; a potential health risk level identified for such economic entities equals 1.11∙10-3 – 0.17 and 1.0∙10-4 – 9.8∙10-4 accordingly
Pan-Eurasian Experiment (PEEX) Program : An Overview of the First 5 Years in Operation and Future Prospects
The Pan-Eurasian Experiment (PEEX) program was initiated as a bottom-up approach by the researchers coming from Finland and Russia in October 2012. The PEEX China kick off meeting was held in November 2013. During its five years in operation, the program has established a governance structure and delivered a science plan for the Northern Eurasian region. PEEX has also introduced a concept design for a modelling platform and ground-based in situ observation systems for detecting land-atmosphere and ocean-atmosphere interactions. Today, PEEX has an extensive researcher’s network representing research communities coming from the Nordic countries, Russia and China. PEEX is currently carrying out its research activities on a project basis, but is looking for more coordinated funding bases, especially in Russia and in China. The near-future challenge in implementing the PEEX research agenda is to achieve a successful integration and identification of the methodological approaches of the socio-economic research to environmental sciences. Here we give insight into these issues and provide an overview on the main tasks for the upcoming years.The Pan-Eurasian Experiment (PEEX) program was initiated as a bottom-up approach by the researchers coming from Finland and Russia in October 2012. The PEEX China kick off meeting was held in November 2013. During its five years in operation, the program has established a governance structure and delivered a science plan for the Northern Eurasian region. PEEX has also introduced a concept design for a modelling platform and ground-based in situ observation systems for detecting land-atmosphere and ocean-atmosphere interactions. Today, PEEX has an extensive researcher’s network representing research communities coming from the Nordic countries, Russia and China. PEEX is currently carrying out its research activities on a project basis, but is looking for more coordinated funding bases, especially in Russia and in China. The near-future challenge in implementing the PEEX research agenda is to achieve a successful integration and identification of the methodological approaches of the socio-economic research to environmental sciences. Here we give insight into these issues and provide an overview on the main tasks for the upcoming years.The Pan-Eurasian Experiment (PEEX) program was initiated as a bottom-up approach by the researchers coming from Finland and Russia in October 2012. The PEEX China kick off meeting was held in November 2013. During its five years in operation, the program has established a governance structure and delivered a science plan for the Northern Eurasian region. PEEX has also introduced a concept design for a modelling platform and ground-based in situ observation systems for detecting land-atmosphere and ocean-atmosphere interactions. Today, PEEX has an extensive researcher’s network representing research communities coming from the Nordic countries, Russia and China. PEEX is currently carrying out its research activities on a project basis, but is looking for more coordinated funding bases, especially in Russia and in China. The near-future challenge in implementing the PEEX research agenda is to achieve a successful integration and identification of the methodological approaches of the socio-economic research to environmental sciences. Here we give insight into these issues and provide an overview on the main tasks for the upcoming years.Peer reviewe
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EPMA-World Congress 2015: Bonn, Germany. 3-5 September 2015
Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of IDO in a murine model of gingivitis: predictive and therapeutic potentials Babak Baban, Jun Yao Liu, Xu Qin, Tailing Wang, Mahmood S. Mozaffari A6 Specific diets for personalised treatment of diabetes type 2 Viktoriia V. Bati, Tamara V. Meleshko, Olga B. Levchuk, Nadiya V. Boyko A7 Towards personalized physiotherapeutic approach Joanna Bauer, Ewa Boerner, Halina Podbielska A8 Cells, animal, SHIME and in silico models for detection and verification of specific biomarkers of non-communicable chronic diseases Alojz Bomba, Viktor O. Petrov, Volodymyr G. Drobnych, Rostyslav V. Bubnov, Oksana M. Bykova, Nadiya V. Boyko A9 INTERACT-chronic care model: Self-treatment by patients with decision support e-Health solution Hans-Peter Brunner-La Rocca, Lutz Fleischhacker, Olga Golubnitschaja, Frank Heemskerk, Thomas Helms, Tiny Jaarsma, Judita Kinkorova, Jan Ramaekers, Peter Ruff, Ivana Schnur, Emilio Vanoli, Jose Verdu A10 PPPM in cardiovascular medicine in 2015 Hans-Peter Brunner-La Rocca A11 Magnetic resonance imaging of nanoparticles in mice, potential for theranostic and contrast media development – pilot results Rostyslav V. Bubnov, Sergiy A. Grabovetskyi, Olena M. Mykhalchenko, Natalia O. Tymoshok, Oleksandr B. Shcherbakov, Igor P. Semeniv, Mykola Y. Spivak A12 Ultrasound diagnosis for diabetic neuropathy - comparative study Rostyslav V. Bubnov, Tetyana V. Ostapenko A13 Ultrasound for stratification patients with diabetic foot ulcers for prevention and personalized treatment - pilot results Rostyslav V. Bubnov, Nazarii M. Kobyliak, Nadiya M. Zholobak, Mykola Ya. Spivak A14 Project ImaGenX – designing and executing a questionnaire on environment and lifestyle risk of breast cancer John Paul Cauchi A15 Genomics – a new structural brand of predictive, preventive and personalized medicine or the new driver as well? Dmitrii Cherepakhin, Marina Bakay, Artem Borovikov, Sergey Suchkov A16 Survey of questionnaires for evaluation of the quality of life in various medical fields Barbara Cieślik, Agnieszka Migasiewicz, Maria-Luiza Podbielska, Markus Pelleter, Agnieszka Giemza, Halina Podbielska A17 Personalized molecular treatment for muscular dystrophies Sebahattin Cirak A18 Secondary mutations in circulating tumour DNA for acquired drug resistance in patients with advanced ALK + NSCLC Marzia Del Re, Paola Bordi, Valentina Citi, Marta Palombi, Carmine Pinto, Marcello Tiseo, Romano Danesi A19 Recombinant species-specific FcεRI alpha proteins for diagnosis of IgE-mediated allergies in dogs, cats and horses Lukas Einhorn, Judit Fazekas, Martina Muhr, Alexandra Schoos, Lucia Panakova, Ina Herrmann, Krisztina Manzano-Szalai, Kumiko Oida, Edda Fiebiger, Josef Singer, Erika Jensen-Jarolim A20 Global methodology for developmental neurotoxicity testing in humans and animals early and chronically exposed to chemical contaminants Arpiné A. Elnar, Nadia Ouamara, Nadiya Boyko, Xavier Coumoul, Jean-Philippe Antignac, Bruno Le Bizec, Gauthier Eppe, Jenny Renaut, Torsten Bonn, Cédric Guignard, Margherita Ferrante, Maria Liusa Chiusano, Salvatore Cuzzocrea, Gerard O'Keeffe, John Cryan, Michelle Bisson, Amina Barakat, Ihsane Hmamouchi, Nasser Zawia, Anumantha Kanthasamy, Glen E. Kisby, Rui Alves, Oscar Villacañas Pérez, Kim Burgard, Peter Spencer, Norbert Bomba, Martin Haranta, Nina Zaitseva, Irina May, Stéphanie Grojean, Mathilde Body-Malapel, Florencia Harari, Raul Harari, Kristina Yeghiazaryan, Olga Golubnitschaja, Vittorio Calabrese, Christophe Nemos, Rachid Soulimani A21 Mental indicators at young people with attributes hypertension and pre-hypertension Maria E. Evsevyeva, Elena A. Mishenko, Zurida V. Kumukova, Evgeniy V. Chudnovsky, Tatyana A. Smirnova A22 On the approaches to the early diagnosis of stress-induced hypertension in young employees of State law enforcement agencies Maria E. Evsevyeva, Ludmila V. Ivanova, Michail V. Eremin, Maria V. Rostovtseva A23 Сentral aortic pressure and indexes of augmentation in young persons in view of risk factors Maria E. Evsevyeva, Michail V. Eremin, Vladimir I. Koshel, Oksana V. Sergeeva, Nadesgda M. Konovalova A24 Breast cancer prediction and prevention: Are reliable biomarkers in horizon? Shantanu Girotra, Olga Golubnitschaja A25 Flammer Syndrome and potential formation of pre-metastatic niches: A multi-centred study on phenotyping, patient stratification, prediction and potential prevention of aggressive breast cancer and metastatic disease Olga Golubnitschaja, Manuel Debald, Walther Kuhn, Kristina Yeghiazaryan, Rostyslav V. Bubnov, Vadym M. Goncharenko, Ulyana Lushchyk, Godfrey Grech, Katarzyna Konieczka A26 Innovative tools for prenatal diagnostics and monitoring: improving individual pregnancy outcomes and health-economy in EU Olga Golubnitschaja, Jan Jaap Erwich, Vincenzo Costigliola, Kristina Yeghiazaryan, Ulrich Gembruch A27 Immunohistochemical assessment of APUD cells in endometriosis Vadym M. Goncharenko, Vasyl O. Beniuk, Olga V. Kalenska, Rostyslav V. Bubnov A28 Updating personalized management algorithm of endometrial hyperplasia in pre-menopause women Vadym M. Goncharenko, Vasyl O. Beniuk, Rostyslav V. Bubnov, Olga Melnychuk A29 The personified treatment approach of polimorbid patients with periodontal inflammatory diseases Irina A. Gorbacheva, Lyudmila Y. Orekhova, Vadim V. Tachalov A30 Ukrainian experience in hybrid war – the challenge to update algorithms for personalized care and early prevention of different military injuries Olena I. Grechanyk, Rizvan Ya. Abdullaiev, Rostyslav V. Bubnov A31 Tear fluid biomarkers: a comparison of tear fluid sampling and storage protocols Suzanne Hagan, Eilidh Martin, Ian Pearce, Katherine Oliver A32 The correlation of dietary habits with gingival problems during menstruation Cenk Haytac, Fariz Salimov, Servin Yoksul, Anatoly A. Kunin, Natalia S. Moiseeva A33 Genomic medicine in a contemporary Spanish population of prostate cancer: our experience Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara, Antonia Angulo, Francisco Javier Machuca Santa-Cruz A34 Challenges, opportunities and collaborations for personalized medicine applicability in uro-oncological disease Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara A35 Metabolic hallmarks of cancer as targets for a personalized therapy John Ionescu A36 Influence of genetic polymorphism as a predictor of the development of periodontal disease in patients with gastric ulcer and 12 duodenal ulcer Alfiya Z. Isamulaeva, Anatoly A. Kunin, Shamil Sh. Magomedov, Aida I. Isamulaeva A37 Challenges in diabetic macular edema Tatjana Josifova A38 Overview of the EPMA strategies in laboratory medicine relevant for PPPM Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja, Vincenzo Costigliola A39 EPMA initiative for effective organization of medical travel: European concepts and criteria Vincenzo Costigliola, Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja A40 Design and innovation in e-textiles: implications for PPPM Anthony Kent, Tom Fisher, Tilak Dias A41 Biobank in Pilsen as a member of national node BBMRI_CZ Judita Kinkorová, Ondřej Topolčan A42 Big data in personalized medicine: hype and hope Matthias Kohl A43 The 3P approach as the platform of the European Dentistry Department (DPPPD) Anatoly A. Kunin, Natalia S. Moiseeva A44 The endometrium cytokine patterns for predictive diagnosis of proliferation severity and cancer prevention Andrii I. Kurchenko, Vasyl A. Beniuk, Vadym M. Goncharenko, Rostyslav V. Bubnov, Nadiya V. Boyko, Andriy M. Strokan A45 A monocyte-based in-vitro system for testing individual responses to the implanted material: future for personalized implant construction Julia Kzhyshkowska, Alexandru Gudima, Ksenia S. Stankevich, Victor D. Filimonov4, Harald Klüter, Evgeniya M. Mamontova, Sergei I. Tverdokhlebov A46 Prediction and prevention of adverse health effects by meteorological factors: Biomarker patterns and creation of a device for self-monitoring and integrated care Ulyana B. Lushchyk, Viktor V. Novytskyy, Igor P. Babii, Nadiya G. Lushchyk, Lyudmyla S. Riabets, Ivanna I. Legka A47 Targeting "disease signatures" towards personalized healthcare Mira Marcus-Kalish, Alexis Mitelpunkt, Tal Galili, Neta Shachar, Yoav Benjamini A48 Influence of the skin imperfection on the personal quality of life and possible tools for objective diagnosis Agnieszka Migasiewicz, Markus Pelleter, Joanna Bauer, Ewelina Dereń, Halina Podbielska A49 The new direction in caries prevention based on the ultrastructure of dental hard tissues and filling materials Natalia S. Moiseeva, Anatoly A. Kunin, Dmitry A. Kunin A50 The use of LED radiation in prevention of dental diseases Natalia S. Moiseeva, Yury A. Ippolitov, Dmitry A. Kunin, Alexei N. Morozov, Natalia V. Chirkova, Nakhid T. Aliev A51 Status of endothelial progenitor cells in diabetic nephropathy: predictive and preventive potentials Mahmood S. Mozaffari, Jun Yao Liu, Babak Baban A52 The status of glucocorticoid-induced leucine zipper protein in salivary gland in Sjögren’s syndrome: predictive and personalized treatment potentials Mahmood S. Mozaffari, Jun Yao Liu, Rafik Abdelsayed, Xing-Ming Shi, Babak Baban A53 Maximal aerobic capacity - important quality marker of health Jaroslav Novák, Milan Štork, Václav Zeman A54 The EMPOWER project: laboratory medicine and Horizon 2020 Wytze P. Oosterhuis, Elvar Theodorsson A55 Personality profile manifestations in patient’s attitude to oral care and adherence to doctor’s prescriptions Lyudmila Y. Orekhova, Tatyana V. Kudryavtseva, Elena R. Isaeva, Vadim V. Tachalov, Ekaterina S. Loboda A56 Results of an European survey on personalized medicine addressed to directions of laboratory medicine Mario Pazzagli, Francesca Malentacchi, Irene Mancini, Ivan Brandslund, Pieter Vermeersch, Matthias Schwab, Janja Marc, Ron H.N. van Schaik, Gerard Siest, Elvar Theodorsson, Chiara Di Resta A57 MCI or early dementia predictive speech based diagnosis techniques Matus Pleva, Jozef Juhar A58 Personalized speech based mobile application for eHealth Matus Pleva, Jozef Juhar A59 Circulating tumor cell-free DNA as the biomarker in the management of cancer patients Jiří Polívka jr., Filip Janků, Martin Pešta, Jan Doležal, Milena Králíčková, Jiří Polívka A60 Complex stroke care – educational programme in Stroke Centre University Hospital Plzen Jiří Polívka, Alena Lukešová, Nina Müllerová, Petr Ševčík, Vladimír Rohan A61 Sleep apnea and sleep fragmentation contribute to brain aging Kneginja Richter, Lence Miloseva, Günter Niklewski A62 Personalised approach for sleep disturbances in shift workers Kneginja Richter, Jens Acker, Guenter Niklewski A63 Medical travel and innovative PPPM clusters: new concept of integration Olga Safonicheva, Vincenzo Costigliola A64 Medical travel and women health Olga Safonicheva A65 Continuity of generations in the training of specialists in the field of reconstructive microsurgery Maxim Sautin, Janna Sinelnikova, Sergey Suchkov A66 Telemonitoring of stroke patients – empirical evidence of individual risk management results from an observational study in Germany Songül Secer, Stephan von Bandemer A67 Women’s increasing breast cancer risk with n-6 fatty acid intake explained by estrogen-fatty acid interactive effect on DNA damage: implications for gender-specific nutrition within personalized medicine Niva Shapira A68 Cytobacterioscopy of the gingival crevicular fluid as a method for preventive diagnosis of periodontal diseases Aleksandr Shcherbakov, Anatoly A. Kunin, Natalia S. Moiseeva A69 Use of specially treated composites in dentistry to avoid violations of aesthetics Bogdan R. Shumilovich, Zhanna Lipkind, Yulia Vorobieva, Dmitry A. Kunin, Anastasiia V. Sudareva A70 National eHealth system – platform for preventive, predictive and personalized diabetes care Ivica Smokovski, Tatjana Milenkovic A72 The common energy levels of Prof. Szent-Györgyi, the intrinsic chemistry of melanin, and the muscle physiopathology. Implications in the context of Preventive, Predictive, and Personalized Medicine Arturo Solís-Herrera, María del Carmen Arias-Esparza, Sergey Suchkov A73 Plurality and individuality of hepatocellular carcinoma: PPPM perspectives Krishna Chander Sridhar, Olga Golubnitschaja A74 Strategic aspects of higher medical education reforms to secure newer educational platforms for getting biopharma professionals matures Maria Studneva, Sihong Song, James Creeden, Мark Мandrik, Sergey Suchkov A75 Overview of the strategies and activities of the European Federation of Clinical Chemistry and Laboratory Medicine, (EFLM) Elvar Theodorsson, EFLM A76 New spectroscopic techniques for point of care label free diagnostics Syed A. M. Tofail A77 Tumor markers for personalized medicine and oncology - the role of Laboratory Medicine Ondřej Topolčan, Judita Kinkorová, Ondřej Fiala, Marie Karlíková, Šárka Svobodová, Radek Kučera, Radka Fuchsová, Vladislav Třeška, Václav Šimánek, Ladislav Pecen, Jan Šoupal, Štěpán Svačina2 A78 Modern medical terminology (MMT) as a driver of the global educational reforms Evgeniya Tretyak, Maria Studneva, Sergey Suchkov A79 Juvenile hypertension; the relevance of novel predictive, preventive and personalized assessment of its determinants Francesca M. Trovato, G. Fabio Martines, Daniela Brischetto, Daniela Catalano, Giuseppe Musumeci, Guglielmo M. Trovato A80 Proteomarkers Biotech George Th. Tsangaris, Athanasios K. Anagnostopoulos A81 Proteomics and mass spectrometry based non-invasive prenatal testing of fetal health and pregnancy complications George Th. Tsangaris, Athanasios K. Anagnostopoulos A82 Integrated Ecosystem for an Integrated Care model for Heart Failure (HF) patients including related comorbidities (ZENITH) José Verdú, German Gutiérrez, Jordi Rovira, Marta Martinez, Lutz Fleischhacker, Donna Green, Arthur Garson, Elena Tamburini, Stefano Cuomo, Juan Martinez-Leon, Teresa Abrisqueta, Hans-Peter Brunner-La Rocca, Tiny Jaarsma, Teresa Arredondo, Cecilia Vera, Giuseppe Fico, Olga Golubnitschaja, Fernando Arribas, Martina Onderco, Isabel Vara, on behalf of ZENITH consortium A83 Predictive, preventive and personalized medicine in diabetes onset and complication (MOSAIC project) José Verdú, Francesco Sambo, Barbara Di Camillo, Claudio Cobelli, Andrea Facchinetti, Giuseppe Fico, Riccardo Bellazzi, Lucia Sacchi, Arianna Dagliati, Daniele Segnani, Valentina Tibollo, Manuel Ottaviano, Rafael Gabriel, Leif Groop, Jacqueline Postma, Antonio Martinez, Liisa Hakaste, Tiinamaija Tuomi, Konstantia Zarkogianni, on behalf of MOSAIC consortium A84 Possibilities for personalized therapy of diabetes using in vitro screening of insulin and oral hypoglycemic agents Igor Volchek, Nina Pototskaya, Andrey Petrov A85 The innovative technology for personalized therapy of human diseases based on in vitro drug screening Igor Volchek, Nadezhda Pototskaya, Andrey Petrov A86 Bone destruction and temporomandibular joint: predictive markers, pathogenetic aspects and quality of life Ülle Voog-Oras, Oksana Jagur, Edvitar Leibur, Priit Niibo, Triin Jagomägi, Minh Son Nguyen, Chris Pruunsild, Dagmar Piikov, Mare Saag A87 Sub-optimal health management – global vision for concepts in medical travel Wei Wang A88 Sub-optimal health management: synergic PPPM-TCAM approach Wei Wang A89 Innovative technologies for minimal invasive diagnostics Andreas Weinhäusel, Walter Pulverer, Matthias Wielscher, Manuela Hofner, Christa Noehammer, Regina Soldo, Peter Hettegger, Istvan Gyurjan, Ronald Kulovics, Silvia Schönthaler, Gabriel Beikircher, Albert Kriegner, Stephan Pabinger, Klemens Vierlinger A90 Rare disease diobanks for personalized medicine Ayşe Yüzbaşıoğlu, Meral Özgüç, Member of EuroBioBank - European Network of DNA, Cell and Tissue Banks for Rare Disease
A multiphase flow in the antroduodenum: some results of the mathematical modelling and computational simulation
This work is devoted to a problem of creation of a multiphase flow model in an antroduodenum that includes the lower part of the stomach and the upper part of the small intestine (duodenum). The mathematical model is developed for the next purposes: description of the process of digestion in normal physiological state and with functional disorders, prediction of the flow characteristics in distinct conditions. The antroduodenum is considered as a complex form canal with moving boundaries. The mathematical statement of the problem includes mass and momentum conservation equations for phases and components as well as initial and boundary conditions with peristaltic movement. To describe secretion and absorption processes we use mass sources/sinks in a layer adjacent to the tract wall. Using computational simulation we got the digestion processes characteristics in dynamic: pH of the medium, components and phases velocities and fractions. In some scenarios with secretory and motor disorders we identified zones of abnormal acidity. The results of the simulation showed that motor functionality of the antrum and pyloric sphincter affect the stomach evacuation. Additionally, the chemical absorption rate is analyzed in scenarios with distinct food parameters (size, viscosity, density)
A multiphase flow in the antroduodenum: some results of the mathematical modelling and computational simulation
This work is devoted to a problem of creation of a multiphase flow model in an antroduodenum that includes the lower part of the stomach and the upper part of the small intestine (duodenum). The mathematical model is developed for the next purposes: description of the process of digestion in normal physiological state and with functional disorders, prediction of the flow characteristics in distinct conditions. The antroduodenum is considered as a complex form canal with moving boundaries. The mathematical statement of the problem includes mass and momentum conservation equations for phases and components as well as initial and boundary conditions with peristaltic movement. To describe secretion and absorption processes we use mass sources/sinks in a layer adjacent to the tract wall. Using computational simulation we got the digestion processes characteristics in dynamic: pH of the medium, components and phases velocities and fractions. In some scenarios with secretory and motor disorders we identified zones of abnormal acidity. The results of the simulation showed that motor functionality of the antrum and pyloric sphincter affect the stomach evacuation. Additionally, the chemical absorption rate is analyzed in scenarios with distinct food parameters (size, viscosity, density)
The Open Corpus of the Veps and Karelian Languages: Overview and Applications
Abstract. A growing priority in the study of Baltic-Finnic languages of the Republic of Karelia has been the methods and tools of corpus linguistics. Since 2016, linguists, mathematicians, and programmers at the Karelian Research Centre have been working with the Open Corpus of the Veps and Karelian Languages (VepKar), which is an extension of the Veps Corpus created in 2009. The VepKar corpus comprises texts in Karelian and Veps, multifunctional dictionaries linked to them, and software with an advanced system of search using various criteria of the texts (language, genre, etc.) and numerous linguistic categories (lexical and grammatical search in texts was implemented thanks to the generator of word forms that we created earlier). A corpus of 3000 texts was compiled, texts were uploaded and marked up, the system for classifying texts into languages, dialects, types and genres was introduced, and the word-form generator was created. Future plans include developing a speech module for working with audio recordings and a syntactic tagging module using morphological analysis outputs. Owing to continuous functional advancements in the corpus manager and ongoing VepKar enrichment with new material and text markup, users can handle a wide range of scientific and applied tasks. In creating the universal national VepKar corpus, its developers and managers strive to preserve and exhibit as fully as possible the state of the Veps and Karelian languages in the 1