77 research outputs found

    Challenges and Opportunities for Public Participation in Urban and Regional Planning during the COVID-19 Pandemic—Lessons Learned for the Future

    Full text link
    The COVID-19 pandemic has spurred significant changes in the fields of economic development, social issues, everyday life, etc. Activities that used to depend on face-to-face communication were firstly suspended and then shifted to new forms of communication. This includes the public participation process in urban and spatial planning. Therefore, this study explores the new domain developed in urban and spatial planning with regard to public participation and surmises future realms in the post-pandemic era. On the occasion of the virtual collaboration platform Cyber Agora organized by the ISOCARP (International Society of City and Regional Planners), chosen participants got together virtually to share, discuss, and compare their practical knowledge in public participation before and during COVID-19. In addition, they addressed the potential benefits of shifting from traditional to virtual participation and potential benefits in the post-COVID-19 era. Considering the collected data and understanding them in the light of the available literature, this study concludes that the application of a combined approach (using both traditional and virtual modes of participation) is recommended because it would enable a larger number and higher diversity of participants. The study also elaborates particular modes of virtual participation with the pros and cons of their use in a particular context.</jats:p

    Patrimonio, turismo y territorio en la Sierra de las Nieves

    Get PDF
    El libro al que pertenece este capítulo ha sido financiado por la Universidad de Málaga y la BUMA dispone de un ejemplar del mismo, depositado en la Biblioteca de Arquitectura y Bellas Artes.Este documento refleja el enfoque de la asignatura "Patrimonio, Turismo y Territorio" en la Escuela de Arquitectura de Málaga. Tras exponer su contexto y su metodogía docente teórica y práctica, el texto se centra en el ejercicio desarrollado por los alumnos, durante el curso 2015-16, en la red de municipios que conforman la Sierra de las Nieves. Los trabajos de estos estudiantes de quinto curso constaron de una parte de investigación y otra de propuesta de intervención y fueron tutorizados por seis profesores pertenecientes a diferentes Áreas de Conocimiento del Departamento Arte y Arquitectura. Esto permite realizar una crítica y autoevaluación de los resultados obtenidos y demostrar el gran valor que la exposición de estos proyectos a los representantes políticos supuso para establecer líneas de investigación y transferencias futuras entre la Universidad y dicha Mancomunidad. Gracias a lo cual, se plantea la creación de un laboratorio de estudio permanente, ubicado en el propio territorio y conformado por estudiantes, profesores de la asignatura y representantes locales

    Table of Contents

    Get PDF
    Chromosome errors, or aneuploidy, affect an exceptionally high number of human conceptions, causing pregnancy loss and congenital disorders. Here, we have followed chromosome segregation in human oocytes from females aged 9 to 43 years and report that aneuploidy follows a U-curve. Specific segregation error types show different age dependencies, providing a quantitative explanation for the U-curve. Whole-chromosome nondisjunction events are preferentially associated with increased aneuploidy in young girls, whereas centromeric and more extensive cohesion loss limit fertility as women age. Our findings suggest that chromosomal errors originating in oocytes determine the curve of natural fertility in humans. [Abstract copyright: Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

    Whole genome analysis reveals aneuploidies in early pregnancy loss in the horse

    Get PDF
    The first 8 weeks of pregnancy is a critical time, with the majority of pregnancy losses occurring during this period. Abnormal chromosome number (aneuploidy) is a common finding in human miscarriage, yet is rarely reported in domestic animals. Equine early pregnancy loss (EPL) has no diagnosis in over 80% of cases. The aim of this study was to characterise aneuploidies associated with equine EPL. Genomic DNA from clinical cases of spontaneous miscarriage (EPLs; 14–65 days of gestation) and healthy control placentae (various gestational ages) were assessed using a high density genotyping array. Aneuploidy was detected in 12/55 EPLs (21.8%), and 0/15 healthy control placentae. Whole genome sequencing (30X) and digital droplet PCR (ddPCR) validated results. The majority of these aneuploidies have never been reported in live born equines, supporting their embryonic/fetal lethality. Aneuploidies were detected in both placental and fetal compartments. Rodents are currently used to study how maternal ageing impacts aneuploidy risk, however the differences in reproductive biology is a limitation of this model. We present the first evidence of aneuploidy in naturally occurring equine EPLs at a similar rate to human miscarriage. We therefore suggest the horse as an alternative to rodent models to study mechanisms resulting in aneuploid pregnancies

    Parameter heterogeneity, persistence and cross-sectional dependence: new insights on fiscal policy reaction functions for the Euro area

    Get PDF
    A number of novelties have emerged in the study of the discretionary fiscal policy within the Euro area during the last decade. Among the others, the availability of up-to-date information on fiscal indicators for the years following the Great Recession, the introduction of cutting-edge econometric methods, and a renewed interest about the sustainability of fiscal policy and public debt. The aim of this paper is to address the challenges posed by the estimation of the discretionary fiscal reaction function for the Euro area. We exploit recently introduced testing and estimation strategies for heterogeneous dynamic panels with cross-sectional dependence and propose a new parsimonious approach. Using real-time data over the period 1996-2016, we investigate whether the fiscal policy reaction function is still a benchmark after the Great Recession. We find evidence of strong cross-sectional dependence in the panel, and clear support to a valid cointegration relationship among the main determinants of the function. Newly added covariates, such interest rate spreads, come out to play a relevant role in explaining discretionary actions
    corecore