58 research outputs found

    A Collaborative tool to prevent fraudulent usage of financial cards

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    Thesis submitted in partial fulfillment of the requirements for the Degree of Master of Science in Information Systems Security (MSc.ISS) at Strathmore UniversityTechnology usage has advanced a great deal in banking and telecommunication sectors. With the continuous improving infrastructures in information technology, new technological dimensions have been opened up to ease processes in these sectors, for example people do not travel to pass communication, to shop and in banking people do not necessarily walk in to the banks to facilitate their financial transactions. Despite this advancement there are dire consequences of possible fraud or crime when we lose our banking identity documents and financial cards. Compromised, lost and stolen credit cards, debit cards, SIM cards, identity cards can be used in crimes. Due to vast adoption of this technology it has increased the surface of this kinds of crime, thereby causing financial loses and posing a challenge when tracking and preventing fraudulent events of the compromised financial cards. This study proposes and implements a system that: prevents fraudulent usage of compromised and lost financial identity items. These items include credit cards, debit cards, and SIM cards. The system will work towards assisting the authorities in investigating crime caused by financial cards. The system provides a blacklist API to the card industry, banking, merchant’s systems and individuals to back-list lost financial identity cards, an alert interfaces that reports usage of blacklist financial cards and a comprehensive reporting tool that helps in investigation of the crime. Agile methodology was adopted as the software methodology for the solution development. A prototype was developed to test the proposed solution. The system was populated with the relevant sample data for evaluation and validation

    Contributions of Atlantic Ocean to June - August rainfall over Uganda and Western Kenya

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    This study investigates the contributions of Atlantic Ocean to June-August rainfall over Uganda and western Kenya (KU). The study has utilized the datasets including precipitation from the Global Precipitation Climatology Centre, North Atlantic Oscillation Index (NAOI), South Atlantic Ocean Dipole Index (SAODI), ERA-interim reanalysis, and the Atlantic Ocean Sea Surface Temperature (SST). Singular value decomposition (SVD), composite analysis and correlation analysis are used to achieve the objective of the study. Results show that the recent extreme rainfall events of June - August (JJA) season were experienced in 2007 (above normal) and 2009 (below normal). Further analysis reveals that there are significant coupled modes of variability; the first mode explains 32% whereas the second mode explains 16% of the total covariance. The first SVD mode captures the positive phase of the South Atlantic Ocean Dipole (SAOD) over Atlantic Ocean. This is associated with positive anomaly of rainfall in most parts of KU. The second SVD mode captures the negative phase of SAOD. The North Atlantic Ocean Index (NAOI) exhibits a significant positive correlation of coefficient ≥ 0.3 with the mean JJA rainfall anomaly over most parts of KU at 95% confidence level. The correlation between the mean JJA rainfall over most parts of KU and NAOI is higher compared to that with SAODI. The dominant moisture source in the region during JJA season is the Atlantic Ocean and the Congo rainforest. The findings from this study provide insight into the influence of Atlantic Ocean on the mean JJA rainfall over KU. The study recommends further research on the utilization of NAOI and SAODI as predictors of the JJA seasonal rainfall over the study area. The production of the JJA seasonal rainfall forecast in the region will enhance better utilization of water resources in the region

    Evaluation of urbanization influences on urban temperature of Nairobi City,Kenya

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    Developing countries are becoming more urbanized leading to modification on climate over the cities. Proper urban atmospheric planning and management are thus fundamental for cities’ sustainability. Urban weather and climate therefore needs continuous monitoring to offer accurate, reliable and timely update of any significant changes. This study examined the long term modification of temperature by urbanization utilizing decadal population data, monthly maximum and minimum temperature and land surface albedo for forty years. The data were subjected to homogeneity test using Short-Cut Bartlett test method that showed both maximum and minimum temperature increasing, though insignificant. Urbanization is evidenced by the reducing land surface albedo and increasing population. The study revealed the influence of urbanization on urban climate. The increase in temperatures is harmful to human comfort. Practical approaches, such as increasing the urban for-est cover and a proper planning of the cities,have been suggested to help prevent further modification of weather and urban climate by urbanization. The findings of this work are thus important for multi-sectoral use in the Kenyan cities

    Feasibility, acceptability, effect, and cost of integrating counseling and testing for HIV within family planning services in Kenya

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    FRONTIERS supported the Division of Reproductive Health and the National AIDS and STI Control Program of the Kenya Ministry of Health to design, implement, and compare two models of integrating counseling and testing (CT) for HIV within family planning (FP) services in terms of their feasibility, acceptability, cost, and effect on the voluntary use of CT, as well as the quality of FP services. The study demonstrated that both models were feasible and acceptable to providers and to clients as means of integrating and linking HIV prevention counseling, condom promotion, and counseling and testing with FP services, and are effective in increasing quality of care and service utilization. Drawing from the lessons learned, the report outlines a number of key programmatic recommendations for institutionalizing and scaling up this approach. Lessons from this study were presented at several national and international workshops and conferences

    Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review

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    BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids. Structural and functional alterations resulting from such changes may persist throughout life and have been associated with diverse diseases. One system that could be particularly sensitive to fetal glucocorticoid overexposure is the hypothalamic-pituitary-adrenal (hpa) axis. Many human studies have investigated this possibility, but a systematic review to identify consistent, emergent findings is lacking. METHODS: We systematically review 49 human studies, assessing the effects of intrauterine exposure to synthetic glucocorticoids on fetal, neonate, and infant hpa function. RESULTS: Study quality varied considerably, but the main findings held true after restricting the analyses to higher-quality studies: intrauterine exposure to synthetic glucocorticoids reduces offspring hpa activity under unstimulated conditions after pain but not pharmacological challenge. Although reduced unstimulated hpa function appears to recover within the first 2 wk postpartum, blunted hpa reactivity to pain is likely to persist throughout the first 4 months of life. There is some evidence that the magnitude of the effects is correlated with the total amount of glucocorticoids administered and varies with the time interval between glucocorticoid exposure and hpa assessment. CONCLUSIONS: This systematic review has allowed the demonstration of the way in which intrauterine exposure to various regimens of synthetic glucocorticoids affects various forms of hpa function. As such, it guides future studies in terms of which variables need to be focused on in order to further strengthen the understanding of such therapy, whilst continuing to profit from its clinical benefits

    Selective Breeding for a Behavioral Trait Changes Digit Ratio

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    The ratio of the length of the second digit (index finger) divided by the fourth digit (ring finger) tends to be lower in men than in women. This 2D∶4D digit ratio is often used as a proxy for prenatal androgen exposure in studies of human health and behavior. For example, 2D∶4D ratio is lower (i.e. more “masculinized”) in both men and women of greater physical fitness and/or sporting ability. Lab mice have also shown variation in 2D∶4D as a function of uterine environment, and mouse digit ratios seem also to correlate with behavioral traits, including daily activity levels. Selective breeding for increased rates of voluntary exercise (wheel running) in four lines of mice has caused correlated increases in aerobic exercise capacity, circulating corticosterone level, and predatory aggression. Here, we show that this selection regime has also increased 2D∶4D. This apparent “feminization” in mice is opposite to the relationship seen between 2D∶4D and physical fitness in human beings. The present results are difficult to reconcile with the notion that 2D∶4D is an effective proxy for prenatal androgen exposure; instead, it may more accurately reflect effects of glucocorticoids, or other factors that regulate any of many genes

    The Origin of Intraspecific Variation of Virulence in an Eukaryotic Immune Suppressive Parasite

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    Occurrence of intraspecific variation in parasite virulence, a prerequisite for coevolution of hosts and parasites, has largely been reported. However, surprisingly little is known of the molecular bases of this variation in eukaryotic parasites, with the exception of the antigenic variation used by immune-evading parasites of mammals. The present work aims to address this question in immune suppressive eukaryotic parasites. In Leptopilina boulardi, a parasitic wasp of Drosophila melanogaster, well-defined virulent and avirulent strains have been characterized. The success of virulent females is due to a major immune suppressive factor, LbGAP, a RacGAP protein present in the venom and injected into the host at oviposition. Here, we show that an homologous protein, named LbGAPy, is present in the venom of the avirulent strain. We then question whether the difference in virulence between strains originates from qualitative or quantitative differences in LbGAP and LbGAPy proteins. Results show that the recombinant LbGAPy protein has an in vitro GAP activity equivalent to that of recombinant LbGAP and similarly targets Drosophila Rac1 and Rac2 GTPases. In contrast, a much higher level of both mRNA and protein is found in venom-producing tissues of virulent parasitoids. The F1 offspring between virulent and avirulent strains show an intermediate level of LbGAP in their venom but a full success of parasitism. Interestingly, they express almost exclusively the virulent LbGAP allele in venom-producing tissues. Altogether, our results demonstrate that the major virulence factor in the wasp L. boulardi differs only quantitatively between virulent and avirulent strains, and suggest the existence of a threshold effect of this molecule on parasitoid virulence. We propose that regulation of gene expression might be a major mechanism at the origin of intraspecific variation of virulence in immune suppressive eukaryotic parasites. Understanding this variation would improve our knowledge of the mechanisms of transcriptional evolution currently under active investigation

    Coconut lethal yellowing diseases: a phytoplasma threat to palms of global economic and social significance

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    The recent discovery of Bogia coconut syndrome in Papua New Guinea (PNG) is the first report of a lethal yellowing disease (LYD) in Oceania. Numerous outbreaks of LYDs of coconut have been recorded in the Caribbean and Africa since the late Nineteenth century and have caused the death of millions of palms across several continents during the Twentieth century. Despite the severity of economic losses, it was only in the 1970s that the causes of LYDs were identified as phytoplasmas, a group of insect-transmitted bacteria associated with diseases in many other economically important crop species. Since the development of polymerase chain reaction (PCR) technology, knowledge of LYDs epidemiology, ecology and vectors has grown rapidly. There is no economically viable treatment for LYDs and vector-based management is hampered by the fact that vectors have been positively identified in very few cases despite many attempted transmission trials. Some varieties and hybrids of coconut palm are known to be less susceptible to LYD but none are completely resistant. Optimal and current management of LYD is through strict quarantine, prompt detection and destruction of symptomatic palms, and replanting with less susceptible varieties or crop species. Advances in technology such as loop mediated isothermal amplification (LAMP) for detection and tracking of phytoplasma DNA in plants and insects, remote sensing for identifying symptomatic palms, and the advent of clustered regularly interspaced short palindromic repeats (CRISPR)-based tools for gene editing and plant breeding are likely to allow rapid progress in taxonomy as well as understanding and managing LYD phytoplasma pathosystems

    Immune stress in late pregnant rats decreases length of gestation and fecundity, and alters later cognitive and affective behaviour of surviving pre-adolescent offspring

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    Immune challenge during pregnancy is associated with preterm birth and poor perinatal development. The mechanisms of these effects are not known. 5α-Pregnan-3α-ol-20-one (3α,5α-THP), the neuroactive metabolite of progesterone, is critical for neurodevelopment and stress responses, and can influence cognition and affective behaviours. To develop an immune challenge model of preterm birth, pregnant Long–Evans rat dams were administered lipopolysaccharide [LPS; 30 μg/kg/ml, intraperitoneal (IP)], interleukin-1β (IL-1β; 1 μg/rat, IP) or vehicle (0.9% saline, IP) daily on gestational days 17–21. Compared to control treatment, prenatal LPS or IL-1β reduced gestational length and the number of viable pups born. At 28–30 days of age, male and female offspring of mothers exposed to prenatal IL-1β had reduced cognitive performance in the object recognition task compared to controls. In females, but not males, prenatal IL-1β reduced anxiety-like behaviour, indicated by entries to the centre of an open field. In the hippocampus, progesterone turnover to its 5α-reduced metabolites was lower in prenatally exposed IL-1β female, but not in male offspring. IL-1β-exposed males and females had reduced oestradiol content in hippocampus, medial prefrontal cortex and diencephalon compared to controls. Thus, immune stress during late pregnancy reduced gestational length and negatively impacted birth outcomes, hippocampal function and central neurosteroid formation in the offspring
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