Describing many-body localized systems in thermal environments

In this work we formulate an efficient method for the description of fully many-body localized systems in weak contact with thermal environments at temperature T. The key idea is to exploit the representation of the system in terms of quasi-local integrals of motion (l-bits) to efficiently derive the generator for the quantum master equation in Born-Markov approximation. We, moreover, show how to compute the steady state of this equation efficiently by using quantum-jump Monte-Carlo techniques as well as by deriving approximate kinetic equations of motion. As an example, we consider a one-dimensional disordered extended Hubbard model for spinless fermions, for which we derive the l-bit representation approximately by employing a recently proposed method valid in the limit of strong disorder and weak interactions. Coupling the system to a global thermal bath, we study the transport between two leads with different chemical potentials at both of its ends. We find that the temperature-dependent current is captured by an interaction-dependent version of Mott's law for variable range hopping, where transport is enhanced/lowered depending on whether the interactions are attractive or repulsive, respectively. We interpret these results in terms of spatio-energetic correlations between the l-bits

Evaluation of the stability of human erythropoietin in samples for radioimmunoassay

Radioimmunoassays for erythropoietin are limited so far to a few specialized laboratories and this requires transport and storage of samples. We therefore tested the stability of immunoreactive erythropoietin in serum and plasma samples obtained from a uremic and a nonuremic anemic patient. No significant change in the concentration of immunoreactive erythropoietin was found in either serum or plasma samples for up to 14 days of storage. This type of stability was observed no matter whether the samples were stored at room temperature, 4 degrees C, or -20 degrees C. There was no difference between the estimates of erythropoietin in serum and heparinized plasma. Validity of the radioimmunoassay used in this study was demonstrated by parallelism of dilution curves of test specimens and the 2nd International Reference Preparation for erythropoietin and by a close correlation between the immunoreactivity and the bioactivity of the hormone, as assessed in the same samples by the exhypoxic polycythemic mouse bioassay. In conclusion the data obtained clearly indicate that the necessity of storage and transport of clinical samples does not limit the practicability of the radioimmunoassay for erythropoietin