7 research outputs found

    Factors Influencing Public Attitudes towards COVID-19 Vaccination: A Scoping Review Informed by the Socio-Ecological Model

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    Major hindrances to getting a COVID-19 vaccine include vaccine hesitancy, skepticism, refusal, and anti-vaccine movements. Several studies have been conducted on attitudes of the public towards COVID-19 vaccines and the potential influencing factors. The purpose of this scoping review is to summarize the data available on the various factors influencing public attitudes towards COVID-19 vaccination. This scoping review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Statement. PubMed, Embase, Web of Science, and Cochrane Central were searched without restrictions to reclaim all publications on the factors that shape individuals’ attitudes towards COVID19 vaccines from 1 January 2020 to 15 February 2021. Fifty studies were included. The scoping review revealed that the factors influencing public attitudes towards COVID-19 vaccines were embedded within the different levels of the socio-ecological model. These factors included the sociodemographic characteristics of the individuals, individual factors, social and organizational factors. In addition, certain characteristics of COVID-19 vaccines themselves influenced public attitudes towards accepting the vaccines. Understanding various population needs and the factors shaping public attitudes towards the vaccines would support planning for evidence-based multilevel interventions in order to enhance global vaccine uptake

    Nanoparticles visualization and extraction for diagnosis and therapy in nanomedicine

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    Nanomedicine is a rapidly developing field of science that has the potential to treat a wide range of complicated ailments. This paper uses a mouse with an inflamed calf and iron oxide nanoparticles (IO-NPs) attached to the therapeutic medicine and put into the mouse’s eye to investigate drug delivery efficiency. The idea is to track and quantify drug delivered to the inflamed calf of the mouse. A high-resolution MRI approach was used to capture images of the inflammatory calf area. Knowing that iron oxide has a high magnetic strength in MRI, image processing techniques were used to calculate the position and number of IO-NPs linked to the administered medication. This paper proposes an image processing approach for detecting and extracting IO-NPs. The images go through pre-processing steps that includes noise filtering and background removal. IO-NPs are isolated from the surrounding tissues using Otsu’s method. The number of IO-NPs grouped in the region, as well as the quantity of medications supplied to the region of interest, can be estimated using IO-NPs extraction. The findings on nanoparticle detection and extraction appear to be a potential method for estimating the amount of medicine targeting a specific location

    The Prevalence and Trends of the Early Introduction of Cow Milk to Newborns at Tertiary Care Center: A Risk of Atopy

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    Although all health organizations recommend exclusive breastfeeding (EBF), few neonates meet these recommended goals. The early intake of cow milk formulas (CMFs) has been linked to several childhood illnesses, including atopic diseases. Therefore, this study aimed to evaluate the prevalence of early exposure to CMFs in the nursery of a tertiary care hospital in Jeddah, Kingdom of Saudi Arabia. A retrospective review was conducted on the medical records of feeding practices of neonates born in King Abdulaziz University Hospital (KAUH) at Jeddah, Kingdom of Saudi Arabia. Two months from each year (May and December) were selected over the last five years. Approval from the ethical research committee at KAUH was obtained. Eight hundred and ninety-four different neonate files were reviewed. Four hundred and eighty-seven (54.5%) were males. Out of the total of 894, 838 (93.7%) newborns experienced an early introduction to CMFs, 797 (89.1%) received mixed CMF and breast milk, 41 (4.6%) received CMF only, and 56 (6.3%) received exclusive breastfeeding (EBF). Surprisingly, EBF has declined over time, from 39% in May 2016 to 1% in December 2020. The prevalence of early exposure to CMF was very high in newborns at KAUH nursery, and this prevalence was trending upwards. Extensive teaching programs on EBF and allergy prevention for mothers and related health care providers are highly recommende

    Association between health information seeking and behaviour change related to physical activity among Qatari adolescents

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    ABSTRACTThis study aims to assess the influence of used information sources on behaviour change related to physical activity (PA). It analyses secondary data from a nationally representative cross-sectional survey conducted in 2017 among 1050 Qatari adolescents aged 13–19 years. Multivariable logistic regression accounting for survey design examined the association between the outcome (attempt to change PA) and interpersonal, online, traditional, and social media information sources. Adolescents who used information from interpersonal and online sources to attempt changing their behaviour had nine times (95% confidence interval [CI]: 4.15–21.08) and nearly three times (95% CI: 1.50–4.27) higher odds of a change in PA behaviour, respectively. The estimated average marginal effects of using information from interpersonal and online sources were 46-percentage point and 16-percentage point increase in the probability of attempting PA behaviour change, respectively. Policymakers may benefit from this research in designing appropriate PA interventions that adapt multiple delivery approaches

    SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

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    Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population
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