“EXPERIENCIA DE LA HISTERECTOMÍA COMO INDICACIÓN DE URGENTE DURANTE 14 AÑOS ( 1994- 2008 ) EN DOS HOSPITALES DE SEGUNDO NIVEL DE LA SECRETARÍA DE SALUD EN EL ESTADO DE MÉXICO”.

Experiencia de la histerectomía como indicación de urgente durante 14 años (1994- 2008) en dos hospitales de segundo nivel de la secretaría de salud en el estado de México

Ciberbullying en niños y adolescentes desde la perspectiva de género: Una revisión sistemática

El presente trabajo tuvo como objetivo conocer la prevalencia de ciberbullying en niños y adolescentes según su género en los estudios realizados entre el 2011 y el 2021; para esto, se desarrolló una revisión sistemática con un diseño básico teórico. En la búsqueda se incluyeron estudios en español e inglés, publicados en las bases de datos: Redalyc, La referencia, Scielo, Comunicar y ProQuest. Se hallaron 295 estudios, de los cuales se seleccionaron 25 para la revisión principal. Los resultados determinaron que, los varones adoptan el papel de ciberagresor antes que de cibervíctima el 78% de las veces, lo que es inverso en las mujeres. También se concluyó que en el 75% de los casos, el agresor es de mayor grado y edad que la víctima. Por último, se hallaron 2 roles de participación definitivos en el ciberacoso (ciberagresor y cibervíctima), y se incluyó un tercer y cuarto participante (observador y agresor-víctima); además de reportarse más de 2 tipos de ciberbullying en la mayoría de los estudios (acoso sexual, intimidación en redes sociales, suplantación de identidad, etc.)

Cooperative learning of requirements engineering through an international educational scenario enabled by the MOY programme

The International Excellence Campus for Higher Education and Research of the Region of Murcia, and the Mediterranean Office for Youth (MOY) programme are new initiatives that offer opportunities for designing educational activities in which can take part international students enrolled in academic degrees at different universities. Besides, a significant rise in distributed and collaborative software development has been observed in recent years (Global Software Development, GSD), which involves space, time and socio-cultural distances and requires new techniques, tools and practices to meet new challenges and opportunities. In addition, poor requirements are one of the most common causes of project failure in any domain. Projects which devote more resources to Requirements Engineering (RE) result in lower costs and lower deviations of their planning. Therefore, the relevance of education and training the future systems and software professionals in RE activities and techniques, in particular in GSD environments, must be stressed. We have conducted an educational innovation activity based on teaching RE in co-located and GSD contexts. This activity has been carried out in the form of an experiment with students. This paper presents the scenario in which this educational activity is framed as well as some preliminary results of this experiment

Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery

Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues

Circulating non-esterified fatty acids as biomarkers for fat content and composition in pigs

Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat content and fatty acid composition in finishing pigs. Genetic variants that regulate lipid metabolism can also modulate the circulating NEFA. We conducted an experiment with 150 heavy Duroc pigs to evaluate fluctuations in the circulating NEFA composition due to age, fasting duration and two genetic polymorphisms, one in the leptin receptor (LEPR; rs709596309) and one in the stearoyl-CoA desaturase (SCD; rs80912566) gene. Circulating NEFA were more saturated and less monounsaturated than the subcutaneous and intramuscular adipose tissues. Absolute circulating NEFA content was more influenced by fasting duration than age. The SCD polymorphism did not impact NEFA content or composition. The LEPR polymorphism affected the content but not the fatty acid composition. Circulating oleic acid NEFA content after a short fasting was positively correlated with intramuscular fat content and, after a long fasting, with intramuscular oleic acid content. We conclude that circulating NEFA reflect environmental and genetic metabolic changes but are of limited value as biomarkers for intramuscular fat content and fatty acid composition.This Research was founded by the Spanish Ministry of Economy and Competitiveness and the European Union Regional Development Funds (grants AGL2012-33529, AGL2015-65846-R, and RTI2018-101346-B-I00)

The 3D Bioprinted Scaffolds for Wound Healing

Skin tissue engineering and regeneration aim at repairing defective skin injuries and progress in wound healing. Until now, even though several developments are made in this field, it is still challenging to face the complexity of the tissue with current methods of fabrication. In this review, short, state-of-the-art on developments made in skin tissue engineering using 3D bioprinting as a new tool are described. The current bioprinting methods and a summary of bioink formulations, parameters, and properties are discussed. Finally, a representative number of examples and advances made in the field together with limitations and future needs are provided

Tin perovskite solar cells with >1,300 h of operational stability in N2 through a synergistic chemical engineering approach

Despite the promising properties of tin-based halide perovskites, one clear limitation is the fast Sn+2 oxidation. Consequently, the preparation of long-lasting devices remains challenging. Here, we report a chemical engineering approach, based on adding Dipropylammonium iodide (DipI) together with a well-known reducing agent, sodium borohydride (NaBH4), aimed at preventing the premature degradation of Sn-HPs. This strategy allows for obtaining efficiencies (PCE) above 10% with enhanced stability. The initial PCE remained unchanged upon 5 h in air (60% RH) at maximum-power-point (MPP). Remarkably, 96% of the initial PCE was kept after 1,300 h at MPP in N2. To the best of our knowledge, these are the highest reported values for Sn-based solar cells. Our findings demonstrate a beneficial synergistic effect when additives are incorporated, highlight the important role of iodide in the performance upon light soaking, and, ultimately, unveil the relevance of controlling the halide chemistry for future improvement of Sn-based perovskite devices

Membrane-Bound Complement Regulatory Proteins in Breast Cancer: Are they Best Therapeutic Targets?

Breast cancer is one of the most aggressive diseases in women, responsible for thousands of deaths annually and millions of new diagnoses; its treatment presents multiple obstacles due to late diagnosis and the various mechanisms of tumor resistance. In breast cancer the membrane-bound complement regulatory proteins (mCRP) have been proposed as biomarkers of malignant cellular transformation. These are molecules capable of inhibiting therapeutic efficacy, from both antibodies and cytotoxic drugs. Therefore, these proteins are potential targets to increase therapeutic efficacy and avoid cancer progression. We will gather information about mCRP: (i) structural features; (ii) expression levels in breast cancer and relationship with prognosis; (iii) therapeutic resistance mechanisms; and (iv) strategies to down-regulate mCRP in both activity and expression

Effectiveness of double-layered compression therapy against crepe bandage for healing venous ulcers in primary care. Randomized clinical trial

Objetivo: Evaluar si el vendaje de 2 capas es más efectivo que el vendaje de crepé en la cicatrización de úlceras venosas tras 12 semanas de seguimiento. Diseño: Ensayo clínico aleatorizado multicéntrico. Emplazamiento: 22 Centros de Salud de Madrid. Participantes: Mayores de 18 años, con diagnóstico de úlceras venosas. Se aleatorizaron 93 pacientes, 56 en el grupo de doble capa y 37 en crepé. Retiradas: 16 en el grupo de doble capa y 7 en el de crepé. Intervenciones: Grupo control: práctica clínica habitual: tratamiento de la herida y vendaje con crepé. Grupo experimental: misma práctica habitual para tratamiento de la herida y vendaje con doble capa. Mediciones principales: Variable respuesta principal: cicatrización completa a las 12 semanas. Variables secundarias: severidad de las lesiones, calidad de vida, reacciones adversas. Evaluación ciega de la variable respuesta. Resultados: Cicatrización completa: 25 (67%) en el grupo crepé (IC al 95% 50,2-81,9) y 32 (57,1%) en doble capa (IC al 95% 43,2-70,3). Sin diferencias en ambos grupos, RR = 1,10 (IC al 95% 0,864-1,424). La severidad de las úlceras basales se asocia al tiempo de cicatrización, HR = 0,86 (IC al 95% 0,78-0,94). Se objetiva mejora significativa en la calidad de vida total y en las dimensiones cosmesis y estado emocional. No se encuentran diferencias según el vendaje utilizado. Sin reacciones adversas graves en ninguno de los grupos. Conclusiones: No encontramos diferencias significativas en la cicatrización entre los 2 tipos de vendaje. Ambos son apropiados para la cicatrización de las úlceras y para mejorar la calidad de vida.Objective: To evaluate if the two-layer bandage is more effective than the crepe bandage in the healing of venous ulcers after 12 weeks of follow-up. Design: Randomized multicentre controlled clinical trial. Location: 22 Primary Health Centers of Madrid. Participants: Over 18 years old, with diagnosis of venous ulcers. 93 patients were randomized, 56 in the double layer group and 37 in the crepe group. Withdrawals: 16 in double layer group, 7 in crepe group. Interventions: Control group: usual clinical practice: treatment of the wound and bandage with crepe. Experimental group: same usual clinical practice for wound treatment and bandage with double layer. Main measurements: Primary outcome: complete healing at 12 weeks. Secondary outcomes: severity of ulceration, health-related quality of life, adverse events. Blind evaluation of the response variable. Results: Complete healing: in crepe group, 25, 67.5% (95% CI 50.2-81.9) and in double layer group, 32, 57.1% (95% CI 43.2-70.3). No evidence of a difference in both groups, RR = 1.10 (95% CI 0.864-1.424). The basal severity of the ulcers is associated with the healing time. HR = 0.86 (95% CI 0.78-0.94). Our data showed a significant improvement in health-related quality of life, total and in the of cosmesis and emotional dimensions. No evidence of a difference in both groups. We didn’t find serious adverse events in any of the groups. Conclusions: We didn’t find significant differences in the healing between the two bandages evaluated. Both are appropriate for ulcer healing and to improve the health-related quality of life.Financiado por el Ministerio de Ciencia e Innovación, a través del Instituto de Salud Carlos III. PN de I+D+I 2008-2011 Cofinanciado con fondos FEDER (PI13/01975) y la Fundación para la Investigación e Innovación Biosanitaria de Atención Primaria de la Comunidad de Madrid (FIIBAP)

Propuesta en la evaluación de desempeño anual para los asesores comerciales del Grupo Fibratel S.A.S. sede Soacha durante el 2021

Anexo A Tabla 1. Perdidas de Ventas 2020-2021 Grupo Fibratel S.A.S, Anexo B Tabla 2. Rotación de Personal 2020-2021 Grupo Fibratel S.A.S., Anexo C Formato 1. Encuesta Aplicada a la Empresa Fibratel S.A.S, Anexo D Tabla 3: Dimensión autoconciencia, Anexo E Tabla 4: Dimensión de Comunicación, Anexo F Tabla 5: Dimensión del Liderazgo, Anexo G Tabla 6: Dimensión de Clima Organizacional, Anexo H Tabla 7: Percepción del SG SST, Anexo I Tabla 8: Dimensión del Trabajo en equipo, Anexo J Gráficos 1: Autoconciencia, Anexo K Gráficos 2: Comunicación, Anexo L Gráficos 2: Liderazgo, Anexo M Gráficos 3: Clima Organizacional, Anexo N Gráficos 4: Percepción SG SST, Anexo Ñ Gráficos 5: Trabajo en Equipo , Anexo O Gráficos 6: propuesta de cronograma de actividades, Anexo P Gráficos 5: Propuesta de Cronograma de Capacitación, Anexo Q Tabla 9: Recursos NecesariosEl presente trabajo desarrolla el análisis de la situación detectada en la empresa Grupo Fibratel S.A.S. dedicada a la comercialización de productos y servicios de telecomunicaciones para empresas y hogar con Claro Colombia. La empresa indica constantes fallas de calidad del servicio que presta en este último periodo, resultando la migración considerable de clientes y la disminución en gestión de ventas. Como estudiantes del programa de Administración de Empresas, proponemos un modelo de evaluación de desempeño anual para los asesores comerciales de la organización, ya que es un procedimiento sistemático que mide e influye en los atributos, comportamientos y resultados, además permite analizar el clima organizacional para gestionar mejoras en la cultura organizacional, ambiente laboral, competencia y habilidades del talento humano de la empresa. La recolección de la información se genera a través de una investigación cuantitativa donde se aplicó una encuesta a 30 empleados y se concluye con la detención de las falencias en adherencia a la cultura organizacional, acciones con bajos niveles de ética laboral, falta de compromiso, carencia en habilidades como: comunicación, trabajo en equipo y gestión del talento mediante el liderazgo que muestre apoyo constante entre las áreas de la empresa que impacten positivamente el clima organizacional y la productividad de la empresa. Con base en lo anterior se construye la propuesta de planes de acción o recomendaciones para optimizar los procesos y desempeño laboral del talento humano de la empresa y de este modo asumir los nuevos desafíos, crecer en el mercado y obtener mejores resultados.This paper develops the analysis of the situation detected in the company Grupo Fibrate S.A.S. dedicated to the marketing of telecommunications products and services for businesses and homes with Claro Colombia. The company indicates constant failures in the quality of the service it provides in this last period, resulting in a considerable migration of customers and a decrease in sales management. As students of the Business Administration program, we propose an annual performance evaluation model for the commercial advisors of the organization, since it is a systematic procedure that measures and influences the attributes, behaviors and results, in addition it allows to analyze the organizational climate to manage improvements in the organizational culture, work environment, competence and skills of the human talent of the company. The collection of information is generated through a quantitative research where a survey was applied to 30 employees and concludes with the detention of deficiencies in adherence to the organizational culture, actions with low levels of work ethics, lack of commitment, lack of skills such as: communication, teamwork and talent management through leadership that shows constant support among the areas of the company that positively impact the organizational climate and productivity of the company. Based on the above, the proposal of action plans or recommendations to optimize the processes and work performance of the company's human talent and thus take on new challenges, grow in the market and obtain better results is built