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Complete genome sequence of a KI polyomavirus isolated from an otherwise healthy child with severe lower respiratory tract infection.
Authors
Walter N Dehority
Darrell L Dinwiddie
+5 more
Megan M Eickman
Stephen M Gross
Gary P Schroth
Kurt C Schwalm
Stephen A Young
Publication date
1 May 2017
Publisher
UNM Digital Repository
Abstract
Unbiased, deep sequencing of a nasal specimen from an otherwise healthy 13-month-old boy hospitalized in intensive care revealed high gene expression and the complete genome of a novel isolate of KI polyomavirus (KIPyV). Further investigation detected minimal gene expression of additional viruses, suggesting that KIPyV was potentially the causal agent. Analysis of the complete genome of isolate NMKI001 revealed it is different from all previously reported genomes and contains two amino acid differences as compared to the closest virus isolate, Stockholm 380 (EF127908). J. Med. Virol. 89:926-930, 2017. © 2016 Wiley Periodicals, Inc
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University of New Mexico
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Last time updated on 26/11/2020