We report the results of a search for D0-D0bar mixing in D0 -> K+ pi- decays
based on 400 fb^{-1} of data accumulated by the Belle detector at KEKB. Both
assuming CP conservation and allowing for CP violation, we fit the decay-time
distribution for the mixing parameters x' and y', as well as for the parameter
R_D, the ratio of doubly-Cabibbo-suppressed decays to Cabibbo-favored decays.
The 95% confidence level region in the (x'^2,y') plane is obtained using a
frequentist method. Assuming CP conservation, we find x'^2<0.72 x 10^{-3} and
-9.9 x 10^{-3}<y'<6.8 x 10^{-3} at the 95% confidence level; these are the most
stringent constraints on the mixing parameters to date. The no-mixing point
(0,0) has a confidence level of 3.9%. Assuming no mixing, we measure
R_D=(0.377+-0.008+-0.005)%.Comment: 6 pages, 3 figures, 1 table; replaced with the version of Phys. Rev.
Let