Marine 5-thiohistidines as protective molecules from skin damage

Abstract

Introduction Marine environment is a great source of bioactive molecules, whose biological properties and applications are often used especially to prevent skin diseases and aging caused by UVA­exposure. Ovothiols are methyl­5­thiohistidines from marine invertebrates, bacteria, and microalgae, which protect cells from environmental stressors. Recently, we have shown that, ovothiol, isolated from sea urchin eggs, exerts anti­inflammatory and antioxidant activities on human endothelial cells, and exhibits antifibrotic effect in an in vivo model of liver fibrosis.info:eu-repo/semantics/publishedVersio