Harini R.

Hiranya Pintana

Jirapas Sripetchwandee

Nielsen F.

Nipon Chattipakorn

Patchareewan Pannangpetch

Piangkwan Sa-nguanmoo

Siriporn C. Chattipakorn

Wang Y.

Wolff S.P.

Yoswaris Semaming

Brain mitochondrial dysfunction has been demonstrated in diabetic animals with neurodegeneration. Protocatechuic acid (PCA), a major metabolite of anthocyanin, has been shown to exert glycemic control and oxidative stress reduction in the heart. However, its effects on oxidative stress and mitochondrial function in the brain under diabetic condition have never been investigated. We found that PCA exerted glycemic control, attenuates brain mitochondrial dysfunction, and contributes to the prevention of brain oxidative stress in diabetic rats.</jats:p

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Applied Physiology Nutrition and Metabolism

Protocatechuic acid protects brain mitochondrial function in streptozotocin-induced diabetic rats

Protocatechuic acid protects brain mitochondrial function in streptozotocin-induced diabetic rats

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