Silver nanoparticles (AgNPs) are an interesting metal nanoparticle that can be incorporated
into pharmaceutical products, including for diabetic foot ulcers as an antimicrobial agent. Green
synthesis of AgNPs using plant extracts has been drawing much attention as it is simple, eco-friendly,
stable, and cost-effective. This present study was performed to evaluate the potential of three
Indonesian medicinal plant extracts, namely Phyllanthus niruri (PN), Orthosiphon stamineus (OS), and
Curcuma longa (CL), as reducing and capping agents in the green synthesis of AgNPs, and to optimize
their concentrations. Based on the yields and characteristics of the formed nanoparticles, which were
analyzed using a UV-Vis spectrophotometer, particle size analyzer, scanning electron microscope,
and X-ray diffractometer, Phyllanthus niruri extract at a concentration of 0.5% was concluded as the
best extract in the green synthesis of AgNPs. It is thereby a prospective reducing and capping agent
for further scale-up studies
