Background Treatment effectiveness and clinical outcome of patients with cervical carcinoma FIGO stage
IA1 and IA2 are analyzed in three different time period at the Department of Obstetrics
and Gynecology Rijeka, Croatia.
Methods Retrospective analysis of the hospital chart of all cervical cancer patients between 1991 and
2005 was conducted with five-year follow up.
Results Data on cervical cancer distribution by stage and five-year survival are presented. Separately
analyzed age, histology type and treatment modalities in stage FIGO IA1 and IA2 during
three consecutive five-year periods are presented.
Conclusions Conservative surgical approach – conization alone in stage IA1 of the squamous cell carcinoma
is reasonable and safe treatment option for reproductive active women. During
observed periods conization became the most used surgical technique applied in almost
two third of FIGO IA1 cervical cancer patients. Lymph vascular space invasion in stage IA1
lead to adjunct pelvic lymphadenectomy with unclear clinical benefit. In cervical cancer
patients stage IA2 simple hysterectomy and pelvic lymphadenectomy could be accepted as
a standard treatment. In these patients further studies are recommended to evaluate other
less radical surgical techniques – simple and radical trachelectomy with or without pelvic
lymphadenectomy. Radical hysterectomy in both stages IA1 and IA2, based on personal
experience and literature data represents a surgical overtreatment and should be abandoned
