333-338Abnormal lipid profile is a common problem among hypertensive as well as working individuals. The rate of mortality is increasing day-by-day due to cardiovascular problems which occurs due to dyslipidemia. The aim of the present study was to assess the therapeutic role of yoga on lipid profile in Ahmedabad population. Total 50 normal healthy control and 50 individuals with dyslipidemia aged >20 years were enrolled for the present study. They were divided into two groups. Individuals in Group-1 were normal healthy, whereas individuals in Group-2 were dyslipidemics. All participants were subjected to yoga practices (Hathyogic practices - Pranayama, yoga postures and meditation) for the various intervals of 0, 3, 6, 9, and 12 months. Serum lipid profile was estimated for all individuals at different intervals. Before beginning the yoga intervention i.e., at 0 month the levels of Total Cholesterol, Total Triglycerides, LDL-cholesterol and VLDL-cholesterol were significantly high, whereas HDL-cholesterol levels were significantly low. After completion of 12 months yoga intervention a significant reduction was observed in Total Cholesterol, Total Triglycerides, LDL-cholesterol and VLDL-cholesterol as well as a significant elevation of HDL-cholesterol was observed. Yoga (Hathyoga) can be a new added adjuvant and cost effective therapy for the patients with abnormal lipid profile