The assessment of the reliability of Monte Carlo simulations is discussed,
with emphasis on uncertainty quantification and the related impact on
experimental results. Methods and techniques to account for epistemic
uncertainties, i.e. for intrinsic knowledge gaps in physics modeling, are
discussed with the support of applications to concrete experimental scenarios.
Ongoing projects regarding the investigation of epistemic uncertainties in the
Geant4 simulation toolkit are reported.Comment: To be published in the Proceedings of the 13th ICATPP Conference on
Astroparticle, Particle, Space Physics and Detectors for Physics
Applications, Villa Olmo, Como, 3-7 October 201