Spencer S. Eccles Health Sciences Library, University of Utah
Abstract
CRION is a recurrent, isolated, steroid dependent optic neuritis, without any associated neurological deficits or known systemic autoimmune diseases. MOG is a component of myelin and an antigen target in central nervous system demyelinating disease. There is growing evidence that the MOG antibody is linked to multiple central nervous system diseases such as anti-aquaporin-4 (AQP4)-negative NMO spectrum disorder with several phenotypical expressions. Similarly, cases of CRION, have been found to be positive for the MOG antibody
