Each follow-up during the course of tuberculosis treatment currently requires two sputum examinations. However, the incremental yield of the second sputum sample during follow-up of different types of tuberculosis patients has never been determined precisely

Ajay M. V. Kumar

Debashish Kundu

Donald A. Enarson

G Nataraj

Kshitij Khaparde

M Shivakumar

Madhav Rao Deshpande

Marcel Manzi

Monica da Silva Nunes

N Aït-Khaled

Priyakanta Nayak

Puneet Kumar Dewan

Rafael Van den Bergh

Sachin Chandraker

Sreenivas Achuthan Nair

Srinath Satyanarayana

PubMed

Kundu, D

M V Kumar, A

Satyanarayana, S

Dewan, P K

Achuthan Nair, S

Khaparde, K

Nayak, P

Van den Bergh, R

Manzi, M

Enarson, D A

Deshpande, M R

Chandraker, S

MSF Field Research

Can follow-up examination of tuberculosis patients be simplified? A study in Chhattisgarh, India

BackgroundEach follow-up during the course of tuberculosis treatment currently requires two sputum examinations. However, the incremental yield of the second sputum sample during follow-up of different types of tuberculosis patients has never been determined precisely.ObjectivesTo assess the incremental yield of the second sputum sample in the follow-up of tuberculosis patients under the Revised National Tuberculosis Control Programme (RNTCP) in Chhattisgarh, India.MethodologyA record review of tuberculosis (TB) patients registered in 2009 using a structured proforma from two sources, Tuberculosis and Laboratory Register, was undertaken in the six districts of Chhattisgarh, India.ResultsIn smear positive cases, of 10,048 follow-up examinations, 45 (0.5%) were found to be smear positive only on the second sputum when the result of the first sample was negative. In smear negative pulmonary and extra pulmonary TB patients, of 6,206 follow-up smear examinations, 11(0.2%) were found to be smear positive.ConclusionsThe incremental yield of a second smear examination was very low, indicating that examination of one sputum sample is enough during follow-up among TB patients. There is insufficient yield to support sputum smear microscopy for monitoring smear negative pulmonary TB and extra pulmonary TB patients. These results indicate that the follow-up smear microscopy can be substantially simplified with favourable resource implications

Ajay M V Kumar

Donald A Enarson

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Can follow-up examination of tuberculosis patients be simplified? A study in Chhattisgarh, India.

Crossref

Can Follow-Up Examination of Tuberculosis Patients Be Simplified? A Study in Chhattisgarh, India

Incremental yield in sputum smear positivity by examining a second early morning sputum specimen in follow-up patients on DOTS: 7 year analysis of RNTCP laboratory register.

Management of tuberculosis. A guide to the essentials of good practice.

Managing the RNTCP in your area - A training course (Modules 1–4) and (Modules 1–9). Directorate General of Health Services, Ministry of Health and Family Welfare, Government of India.

Organization (2010) Treatment of tuberculosis: guidelines for national programmes. Fourth edition. World Health Organization Document WHO/HTM/TB/2009.420:

Repeated sputum microscopy is not essential for monitoring treatment response.

http://fieldresearch.msf.org/msf/bitstream/10144/295260/1/Kundu+et+al+-+2012+Can+Follow-Up+Examination+of+Tuberculosis+Patients+Be+Simplified.pdf

Can follow-up examination of tuberculosis patients be simplified? A study in Chhattisgarh, India

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MSF Field Research

Directory of Open Access Journals

Crossref