Ryhänen, Tuomas

English

UEF Electronic Publications

17-AAG induces cytoplasmic alpha-synuclein aggregate clearance by induction of autophagy&quot;,

4-Hydroxy-2, 3-Nonenal Activates Activator Protein-1 and Mitogen-Activated Protein Kinases in Rat Pancreatic Stellate Cells&quot;,

4-hydroxynonenal induces apoptosis, NF-kappaB-activation and formation of 8-isoprostane in vascular smooth muscle cells&quot;,

4-Hydroxynonenal prevents NFkappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis&quot;,

4-Hydroxynonenal Triggers Multistep Signal Transduction Cascades for Suppression of Cellular Functions&quot;,

4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes&quot;,

4-Hydroxynonenal: a Membrane Lipid Oxidation Product of Medicinal Interest&quot;,

A BBSome subunit links ciliogenesis, microtubule stability, and acetylation&quot;,

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration&quot;,

A hitchhiker's guide to the human Hsp70 family&quot;,

A molecular chaperone complex at the lysosomal membrane is required for protein translocation&quot;,

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding&quot;,

A receptor for the selective uptake and degradation of proteins by lysosomes&quot;,

A review of mechanisms of circumvention and modulation of chemotherapeutic drug resistance&quot;,

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins&quot;,

A role for local inflammation in the formation of drusen in the aging eye&quot;,

A role for ubiquitin in selective autophagy&quot;,

A2E, a byproduct of the visual cycle&quot;,

A2E, a component of lipofuscin, is pro-angiogenic in vivo&quot;,

A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity&quot;,

Accumulation of large protein fragments in prematurely senescent ARPE-19 cells&quot;,

Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation&quot;,

Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production&quot;,

Activators and target genes of Rel/NF-kappaB transcription factors&quot;,

Adapting proteostasis for disease intervention&quot;,

Age related macular degeneration&quot;,

Age-related changes in the autophagic proteolysis of rat isolated liver cells: effects of antiaging dietary restrictions&quot;,

Age-related decline in chaperone-mediated autophagy&quot;,

Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90&quot;,

Age-related macular degeneration--emerging pathogenetic and therapeutic concepts&quot;,

Age-related macular degeneration: current and novel therapies&quot;,

Age-related macular degeneration&quot;,

Age-related macular degeneration&quot;, The New England

Age-specific prevalence and causes of bilateral and unilateral visual impairment in older Australians:

Ageing-related changes in the in vivo function of rat liver macroautophagy and proteolysis&quot;,

Aggresomes, inclusion bodies and protein aggregation&quot;,

Aging and the ubiquitinome: traditional and non-traditional functions of ubiquitin in aging cells and tissues&quot;,

Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG)&quot;,

Alterations in the chaperone activity of HSP70 in aging organisms&quot;,

Alterations of activity and intracellular distribution of the 20S proteasome in ageing retinal pigment epithelial cells&quot;,

Amyloid in neurodegenerative diseases: Friend or foe?&quot;,

An acetylation site in the middle domain of Hsp90 regulates chaperone function&quot;,

An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation&quot;,

An overview of the molecular mechanism of autophagy&quot;,

Analysis of native forms and isoform compositions of the mouse 90-kDa heat shock protein, HSP90&quot;,

Androgen receptor acetylation site mutations cause trafficking defects, misfolding, and aggregation similar to expanded glutamine tracts&quot;,

AP-1: a double-edged sword in tumorigenesis&quot;,

Apical-to-basolateral transcytosis of photoreceptor outer segments induced by lipid peroxidation products in human retinal pigment epithelial cells&quot;,

ARPE-19, a human retinal pigment epithelial cell line with differentiated properties&quot;,

Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples&quot;,

Assembly, structure, and function of the 26S proteasome&quot;,

Autophagosome-lysosome fusion depends on the pH in acidic compartments in CHO cells&quot;,

Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration&quot;,

Autophagy and metabolism&quot;,

Autophagy and the integrated stress response&quot;,

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection&quot;,

Autophagy fights disease through cellular self-digestion&quot;,

Autophagy gone awry in neurodegenerative diseases&quot;,

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's Disease&quot;,

Autophagy, amyloidogenesis and Alzheimer disease&quot;,

Autophagy: cellular and molecular mechanisms&quot;,

beta-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency&quot;,

Binding of amyloid beta protein to the 20 S proteasome&quot;,

Biogenic 4-hydroxy-2-nonenal activates transcription factor AP-1 but not NFkappa B in cells of the macrophage lineage&quot;,

Causes and prevalence of visual impairment among adults in the United States&quot;,

Cell &quot;self-eating&quot; (autophagy) mechanism in Alzheimer's disease&quot;,

Cell biology: Tubulin acetylation and cell motility&quot;,

Cell-free reconstitution of microautophagic vacuole invagination and vesicle formation&quot;,

Cellular strategies for controlling protein aggregation&quot;,

Changes in Select Redox Proteins of the Retinal Pigment Epithelium in Age-related Macular Degeneration&quot;,

Chaperone machines in action&quot;,

Chaperone-mediated autophagy in aging and disease&quot;,

Chaperone-mediated autophagy: machinery, regulation and biological consequences&quot;,

Chaperone-mediated autophagy&quot;,

Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury&quot;,

Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera&quot;,

Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration&quot;,

Characterization of chronic low-level proteasome inhibition on neural homeostasis&quot;,

Chasing the elusive mammalian microautophagy&quot;,

CHIP is a chaperonedependent E3 ligase that ubiquitylates unfolded protein&quot;,

Clearance of dying ARPE-19 cells by professional and nonprofessional phagocytes in vitro- implications for age-related macular degeneration (AMD)&quot;,

Common causes of vision loss in elderly patients&quot;,

Complement factor H polymorphism and age-related macular degeneration&quot;,

Complement factor H polymorphism in age-related macular degeneration&quot;,

Complement factor H variant increases the risk of age-related macular degeneration&quot;,

Compositional studies of human RPE lipofuscin: mechanisms of molecular modifications&quot;,

Consequences of the selective blockage of chaperone-mediated autophagy&quot;,

Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy&quot;,

Constitutive hsp70 attenuates hydrogen peroxide-induced membrane lipid peroxidation&quot;,

Coomassie blue protein dye-binding assays measure formation of an insoluble protein-dye complex&quot;,

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent&quot;,

Current concepts in the pathogenesis of age-related macular degeneration&quot;,

Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration&quot;,

Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease&quot;,

Decreased proteasome-mediated degradation in T cells from the elderly: A role in immune senescence&quot;,

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance&quot;,

Development and application of Hsp90 inhibitors&quot;,

Dietary supplementation: effects on visual performance and occurrence of AMD and cataracts&quot;,

Differential expression of heat shock protein mRNAs under in vivo glutathione depletion in the mouse retina&quot;,

Differential protein profiling of primary versus immortalized human RPE cells identifies expression patterns associated with cytoskeletal remodeling and cell survival&quot;,

Crosstalk between molecular chaperones, protein aggregation and autophagic degradation in retinal pigment epithelial cells implications for the pathogenesis of age-related macular degeneration

http://epublications.uef.fi/pub/urn_isbn_978-952-61-0558-1/urn_isbn_978-952-61-0558-1.pdf

Crosstalk between molecular chaperones, protein aggregation and autophagic degradation in retinal pigment epithelial cells implications for the pathogenesis of age-related macular degeneration

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