Heinonen, Suvi

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UEF Electronic Publications

10-year safety followup i n pa tie nts w ith lo cal VEGF gene tra nsfe r to isch emi c low er li mb&quot;, Gene Therapy,

7, &quot;Curre nt status of cardiovascula r gene the ra py &quot;,

A model for dia beti c ne phro pathy : Advantages of the indu ci ble cAMP ea rly re presso r tra nsge ni c mouse over the streptozotocin-induced diabetic mouse&quot;,

A mouse model for human atherosclerosis: Long-term histopathological study of lesion development in the aortic arch of apolipoprotein E-deficient (E0) mice&quot;,

A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet&quot;,

A murine model of obesity with accelerated atherosclerosis&quot;,

A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse&quot;,

A novel locus,

A target-mediated model to describe the pharmacokinetics and hemodynamic effects of recombinant human vascular endothelial growth factor in humans&quot;,

Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential Hypertension&quot;,

Accelerated atherosclerosis and premature calcified cartilaginous metaplasia in the aorta of diabetic male Apo E knockout mice can be prevented by chronic treatment with 17β-estradiol&quot;, Atherosclerosis,

Accelerated Glucose Intolerance, Nephropathy, and Atherosclerosis

Accelerated Nephropathy in Diabetic Apolipoprotein E-Knockout Mouse: Role of Advanced Glycation End Products&quot;,

Activation of Vascular Bone Morphogenetic Protein Signaling

Addition of dietary fat to cholesterol in the diets of LDL receptor knockout mice: effects on plasma insulin, lipoproteins, and atherosclerosis&quot;,

Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice.&quot;

Aging Causes Collateral Rarefaction and Increased Severity of Ischemic Injury in Multiple Tissues&quot;,

Ai e l l o ,

Aldose Reductase Deficiency Prevents Diabetes-Induced Blood-Retinal Barrier Breakdown, Apoptosis, and Glial Reactivation in the Retina of db/db Mice&quot;,

Aldose Reductase Protects Against Early Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice&quot;,

An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration&quot;,

Angiogenesis Inhibitors Endostatin or

Angiogenesis, Arteriogenesis, and Diabetes: Paradigm Reassessed?&quot;,

Animal Models of Diabetic Complications Consortium

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree&quot;,

Apolipoprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB- containing plasma lipoproteins&quot;,

Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2 diabetes mellitus&quot;,

Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice&quot;,

Atherogenic Lipoprotein Particles in Atherosclerosis&quot;,

Atherosclerosis — An Inflammatory Disease&quot;,

Atherosclerosis: The Road Ahead&quot;,

Atherosclerotic lesions in the common coronary arteries of ApoE knockout mice&quot;,

Attenuation of Accumulation of Neointimal Lipid by Pioglitazone in Mice Genetically Deficient in Insulin Receptor Substrate-2 and Apolipoprotein E&quot;,

B a r t o n ,

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes&quot;,

Beta-cell failure as a complication of diabetes&quot;,

Biochemistry and molecular cell biology of diabetic complications&quot;,

Biodistribution of adenoviral vector to nontarget tissues after local in vivo gene transfer to arterial wall using intravascular and periadventitial gene delivery methods&quot;,

Biological Therapies for Cardiac Arrhythmias: Can Genes and Cells Replace Drugs and Devices?&quot;,

Biopharmaceutical benchmarks 2010&quot;,

C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis&quot;,

Cardiotoxicity of the new cancer therapeutics – mechanisms of, and approaches to, the problem&quot;,

Cellular and molecular basis of wound healing in diabetes&quot;,

Characterization of atherosclerotic lesions in apo E3-leiden transgenic mice&quot;,

Cigarette Smoking Potentiates Endothelial Dysfunction of Forearm Resistance Vessels in Patients With Hypercholesterolemia: Role of Oxidized LDL&quot;,

Coronary artery disease progression is associated with increased resistance of hearts and myocytes to cardiac insults&quot;,

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine&quot;,

Current Concepts of the Pathogenesis of the Acute Coronary Syndromes&quot;,

D i re cti v e

D o no v a n , J ., A ny a o k u , V ., F l a t he r,

Decreased Efficiency of Adenovirus-Mediated Gene Transfer in Aging Cardiomyocytes&quot;,

Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes&quot;,

Defective Leptin/Leptin Receptor S i g n a l i n g I m p r o v e s R e g u l a t o r y T C e l l I m m u n e R e s p o n s e a n d P r o t e c t s M i c e F r o m Atherosclerosis&quot;, Arteriosclerosis, Thrombosis, and Vascular Biology,

Defining and Defending Murine Models of Plaque Rupture&quot;, Arteriosclerosis, Thrombosis, and Vascular Biology,

Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100&quot;,

Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice&quot;,

Demonstration of all connective tissue elements in a single section; pentachrome stains&quot;,

Diabetes and Atherosclerosis&quot;, JAMA:

Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions&quot;,

Diabetes and Endothelial Dysfunction: A Clinical Perspective&quot;,

Diabetes and Vascular Disease: Pathophysiology, Clinical Consequences, and Medical Therapy: Part I&quot;,

Diabetes Mellitus Activates Signal Transduction Pathways Resulting in Vascular Endothelial Growth Factor Resistance of Human Monocytes&quot;,

Diabetic atherosclerosis mouse models&quot;,

Diabetic Cardiomyopathy: Evidence, Mechanisms, and Therapeutic Implications&quot;,

Diabetic dyslipidaemia&quot;,

Diabetic vascular disease: an experimental objective&quot;,

Diet and Murine Atherosclerosis&quot;,

Diet effects on atherosclerosis in mice&quot;,

Diet-induced diabetes a c t i v a t e s a n o s t e o g e n i c g e n e r e g u l a t o r y p r o g r a m i n t h e a o r t a s o f l o w d e n s i t y l i p o p r o t e i n receptor-deficient mice&quot;,

Effect of Diabetes Mellitus on Formation of Coronary Collateral Vessels&quot;,

Effect of human recombinant vascular endothelial growth factor 165 on progression of atherosclerotic plaque&quot;,

Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: establishment of a combined model and association with heat shock protein 65 immunity&quot;,

Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials&quot;,

Effect of Streptozotocin-Induced Hyperglycemia on Lipid Profiles, Formation of Advanced Glycation Endproducts

Effects of apo E Deficiency on Plasma Lipid Levels in Mice Lacking APOBEC-1&quot;,

Effects of diabetes and CETP expression on diet-induced atherosclerosis in LDL receptordeficient mice&quot;,

Effects of streptozotocininduced diabetes in apolipoprotein AI deficient mice&quot;,

Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer&quot;,

Endothelial Nitric Oxide Synthase Deficiency Produces Accelerated Nephropathy in Diabetic Mice&quot;,

Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes&quot;,

Enhanced cell cycle entry and mitogen-activated protein kinase-signaling and downregulation of matrix metalloproteinase-1 and -3 in human diabetic arterial vasculature&quot;,

Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies&quot;,

Epidemiology of some peripheral arterial findings in diabetic men and women: Experiences from the Framingham study&quot;,

Epidemiology of Type 2 Diabetes Mellitus&quot;

Evidence that triglycerides are an independent coronary heart disease risk factor&quot;,

Expression of Human OSBP-Related

Familial Aggregation of Coronary Artery Calcium

Familial hypercholesterolemia.&quot;

First-phase insulin secretion: does it exist in real life? Considerations on shape and function&quot;,

Food-restriction in obese dyslipidaemic diabetic mice partially restores basal contractility but not contractile reserve&quot;,

From endothelial dysfunction to atherosclerosis&quot;,

G u r t n e r ,

Gene therapy for heart failure&quot;,

Gene transfer as a tool to induce therapeutic vascular growth&quot;,

Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction&quot;,

Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48-/-Lepob/ob mice devoid of ApoE or Ldlr&quot;,

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells&quot;,

Genetic background determines response to hemostasis and thrombosis&quot;,

Genetic linkage of hyperglycemia, body weight and serum amyloid-P in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice&quot;,

Genetics of Type 1 Diabetes: What's Next?&quot;, Diabetes,

Modeling cardiovascular complications of diabetes mellitus development of a new mouse model and evaluation of a gene therapy approach

http://epublications.uef.fi/pub/urn_isbn_978-952-61-0548-2/urn_isbn_978-952-61-0548-2.pdf

Modeling cardiovascular complications of diabetes mellitus development of a new mouse model and evaluation of a gene therapy approach

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