Infant milk formulas: effect of heat treatments on the protein physicochemical properties and the nutritional quality. STLOpenday

Halabi, Amira

English

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Submitted on 4 Jun 2020
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Infant milk formulas: effect of heat treatments on the
protein physicochemical properties and the nutritional
quality
Amira Halabi
To cite this version:
Amira Halabi. Infant milk formulas: effect of heat treatments on the protein physicochemical proper-
ties and the nutritional quality. STLOpendays, Institut National de Recherche Agronomique (INRA).
UMR UMR INRA / AgroCampus Rennes : Science et Technologie du Lait et de l’?uf (1253)., Mar
2019, Rennes, France. ￿hal-02098685￿
Yves LE LOIR - STLO
STLOpen Days
19-21 March 2019
Welcome
Infant milk formulas:
Effect of heat treatment on the protein 
physicochemical properties and the nutritional 
quality
Amira Halabi – ISF/BN Teams
Interaction-Structure-Functionalities / Bioactivity and nutrition
STLOpen Days
19-21 March 2019
2
Socio-economic and scientific contexts
Percentage of infants 0–5 months of age 
exclusively breastfed
UNICEF global databases, 2018
Needs Consequences
Digestibility ?
Protein structural 
modifications
Extend shelf-life
Microbiological 
safety
Heat treatments of infant milk formulas
Adapted from Chatterton et al. 2013
Protein composition of human milk, 
commercial infant milk formulas and 
bovine milk
Whey 
proteins
STLOpen Days
19-21 March 2019
Strategy
3
What are the impacts of heat treatment on the structure and digestion kinetic of proteins of 
infant milk formulas mimicking the protein profile of human milk ?
Heat treatment
Temperature range 
67.5°C-80°C
Infant milk formulas
Three formulas at 1.3% and 5.5% 
of proteins
Formula 1
CN:WP 40:60
Without 
modification
Formula 2
CN:WP 40:60
LF quantity closes to 
that of human milk
Formula 3
CN:WP 40:60
LF and α-LA quantities close 
to those of human milk
CN: caseins
WP: whey proteins
LF: lactoferrin
α-LA: α-lactalbumin
Characterization of heat-
induced aggregates
Protein interaction – Size - Shape
Kinetic of individual whey 
protein denaturation
In vitro protein digestion kinetic 
Protein hydrolysis – Peptide release -
Bioaccessibility
THANK YOU FOR
YOUR ATTENTION
MERCI
Please visit http://www.rennes.inra.fr/stlo_engSTLOpen Days
19-21 March 2019
POSTER 9
4


Infant milk formulas: effect of heat treatments on the protein physicochemical properties and the nutritional quality

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Infant milk formulas: effect of heat treatments on the protein physicochemical properties and the nutritional quality

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