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3T MR Angiography and ASL Perfusion in primary angiitis of the central nervous system

Abstract

Primary angiitis of the central nervous system (PACNS) is a rare and ill-defined disease. Headache and encephalopathy are the most frequent symptoms at onset. Neuroimaging plays an important role in the diagnosis but the pattern of abnormal findings is often not specific and diagnosis required brain biopsy. MRA is a reasonable initial modality in the investigation of suspected CNS vasculitis. 3T MRA offers increased signal to noise ratio with better background suppression, leading to better depiction of the intracranial circulation. We estimate the usefulness of MRA and ASL analysis in the diagnosis of PACNS at 3T

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