Sterilni neutrofilni dermatitis u mačke

Abstract

A 6.7 kg 7 year-old castrated male domestic short hair cat was presented with several dermatological lesions on the ventral abdomen. The skin of the abdomen and inner thighs was affected. Both inner thighs were equally involved. They were covered with thick and folded, “card-board” devitalised skin. Some ulcerative haemorrhagic lesions were coated by greyish pseudomembranes of necrotic epithelium and fibrin. There was a distinctive margin between normal and affected skin. On the abdomen there was patchy erythema and papules. No other skin lesions were found on the rest of the body. Differential diagnoses for the lesions included: drug reaction, erythema multiforme, toxic epidermal necrolysis, vasculitis, and impetigo. Histopathology revealed different lesions: superficial pustules, ulceration and fibrin exudation, pustule disease with hair follicle destruction. There was no evidence of bacteria on cytology and histopathology. All previously prescribed drugs were stopped. On the day after initial proceeding lesions become less haemorrhagic and less thick. On the fourth day skin lesions were dry. Local therapy (povidone iodine) was maintained and the cat was sent home on day 5. Conclusion of case is sterile neutrophilic dermatitis.Kastrirani mačak, kratkodlake domaće pasmine, u dobi od 7 godina, mase 6,7 kilograma dobio je nekoliko lezija na trbušnoj koži. Koža je bila debela i naborana poput kartona. Nekoliko ulcerativnih hemoragičnih lezija bilo je pokriveno sivim pseudomembranoznim nekrotizirajućim epitelom i fibrinom. Granica između normalne i promijenjene kože bila je jasna. Na trbuhu je uočen eritem i papule. Druge lezije na koži nisu uočene. Diferencijalno-dijagnostički u obzir je uzeta reakcija na lijekove, erythema multiforme, toksična epidermalna nekroza, vaskulitis i impetigo. Patohistološkom pretragom uočene su površinske pustule, ulceracija i eksudacija fibrina, destrukcija dlačnih folikula. Citološkom i patohistološkom pretragom nisu uočene bakterije. Sva do tada propisana terapija je prekinuta, dan nakon prvog pregleda lezije su postale manje hemoragične i koža nešto manje zadebljala. Četvrtoga dana kožne lezije bile su suhe, lokalna terapija je nastavljena 1 %-tnim povidone jodom i mačak je pušten na kućnu njegu petoga dana. Postavljena dijagnoza bila je sterilni neutrofilni dermatitis