The tthh production at colliders contain rich information on the nature of
Higgs boson. In this article, we systematically studied its physics at
High-Luminosity Large Hadron Collider (HL-LHC), using exclusive channels with
multiple (≥5) b-jets and one lepton (5b1ℓ), multiple (≥5)
b-jets and opposite-sign di-lepton (5b2ℓ), same-sign di-lepton
(SS2ℓ), multiple leptons (multi-ℓ), and di-tau resonance
(ττ). The scenarios analyzed include: (1) the tthh production in
Standard Model; (2) the tthh production mediated by anomalous cubic Higgs
self-coupling and tthh contact interaction; (3) heavy Higgs (H) production
with ttH→tthh; and (4) pair production of fermionic top partners (T)
with TT→tthh. To address the complication of event topologies and the
mess of combinatorial backgrounds, a tool of Boosted-Decision-Tree was applied
in the analyses. The 5b1ℓ and SS2ℓ analyses define the two most
promising channels, resulting in slightly different sensitivities. For
non-resonant tthh production, a combination of these exclusive analyses
allows for its measurment in the SM with a statistical significance ∼0.9σ (with S/B>1%), and may assist partially breaking the
sensitivity degeneracy w.r.t. the cubic Higgs self-coupling, a difficulty
usually thought to exist in gluon fusion di-Higgs analysis at HL-LHC. These
sensitivities were also projected to future hadron colliders at 27 TeV and 100
TeV. For resonant tthh productions, the heavy Higgs boson in type II
Two-Higgs-Doublet-Model could be efficiently searched for between the mass
thresholds 2mh<mH<2mt and even beyond that, for relatively small
tanβ, while the fermionic top partners in composite Higgs models could
be probed for up to ∼1.5 TeV and ∼1.7 TeV, for Br(T→th)=25%
and 50%, respectively.Comment: 30 pages, 12 figure