Targett, GAT

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LSHTM Research Online

A model for sequestration of the transmission stages of Plasmodium falciparum: adhesion of gametocyte-infected erythrocytes to human bone marrow cells.

Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.

Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection.

Antibodies to variable Plasmodium falciparum infected erythrocyte surface antigens are associated with protection from novel malaria infections.

Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children.

Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

Association between anti-Pfs48/45 reactivity and P. falciparum transmission-blocking activity in sera from Cameroon. Parasite Immunol

CD36-dependent adhesion and knob expression of the transmission stages of Plasmodium falciparum is stage-specific.

Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes.

Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry.

Determination of mosquito bloodmeal pH in situ by ion-selective microelectrode measurement: implications for the regulation of malarial gametogenesis.

Distinct trafficking and localization of STEVOR proteins in three stages of the Plasmodium falciparum life cycle.

Evaluation of the standard membrane feeding assay (SMFA) for the determination of malaria transmission-reducing activity using empirical data.

Gambian children successfully treated with chloroquine can harbour and transmit Plasmodium falciparum gametocytes carrying resistance genes.

Gametocytaemia after Drug Treatment of Asymptomatic Plasmodium falciparum.

Gametocytogenesis of Plasmodium falciparum in vitro: the cell-cycle.

High human malarial infectivity to laboratory-bred Anopheles gambiae in a village in Burkina Faso.

Human malaria parasites in continuous culture.

Improved synchronous production of Plasmodium falciparum gametocytes in vitro.

In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children.

Malaria parasites undergo antigenic variation at high rates in vivo.

Malaria transmission-blocking immunity induced by natural infections of Plasmodium vivax in humans.

Malaria vaccines: are we getting closer? Curr Opin Mol Ther.

Malaria-induced acquisition of antibodies to Plasmodium falciparum variant surface antigens.

Naturally occurring antibodies to an epitope on Plasmodium falciparum gametes detected by monoclonal antibody-based competitive enzyme-linked immunosorbent assay.

Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.

Pfs47, paralog of the male fertility factor Pfs48/45, is a female specific surface protein in Plasmodium falciparum.

Plasmodium falciparum Associated with Severe Childhood Malaria Preferentially Expresses PfEMP1 Encoded by Group A var Genes.

Programmed Transcription of the var Gene Family, but Not of stevor, in Plasmodium falciparum Gametocytes.

PSLAP, a protein with multiple adhesive motifs, is expressed in Plasmodium falciparum gametocytes. Mol Biochem Parasitol.

Radbruch A

Rapid switching to multiple antigenic and adhesive phenotypes in malaria.

Reduction of malaria transmission to Anopheles mosquitoes with a six-dose regimen of Co-artemether.

Stage-dependent toxicity of Nacetyl-glucosamine to Plasmodium falciparum.

Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes.

Synchronization of Plasmodium falciparum gametocytes using an automated suspension culture system.

The addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children delays, but does not prevent treatment failure.

The distribution of Plasmodiumfalciparum in the peripheral blood and bone marrow of Gambian children.

The gametocyteactivating factor xanthurenic acid stimulates an increase in membraneassociated guanylyl cyclase activity in the human malaria parasite Plasmodium falciparum.

Transmission blockade of Plasmodium falciparum malaria by anti-Pfs230-specific antibodies is isotype dependent.

Transmission-reducing immunity is inversely related to age in Plasmodium falciparum gametocyte carriers.

Treatment of malaria in Gambian children with chloroquine plus sulphadoxine-pyrimethamine favours survival and transmission to mosquitoes of multi-drug-resistant Plasmodium falciparum.

Virulence and transmission success of the malarial parasite Plasmodium falciparum.

Vaccines Targeting Vectors

http://researchonline.lshtm.ac.uk/7675/1/pone.0002280.pdf

Vaccines Targeting Vectors

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