This presentation was created in the Fall semester of 2017 while the author served as an intern in the Office of Digital Research and Scholarship at Florida State University, where he researched the ways in which audio-visual media was being utilized in digital humanities projects. Offering a kind of "state of the field," this presentation summarizes the key issues associated with this kind of work while providing an overview of several projects, platforms, and tools used in digital humanities projects dealing with audio-visual materials and collections

Ahmad, Rajai

Asanin, Milika R.

Jozic, Irena

Jozic, Tanja

Lip, Gregory Y. H.

Mihajlovic, Miroslav

Potpara, Tatjana S.

Stankovic, Sanja

The American Journal of Medicine

Tatjana S. Potpara

Miroslav Mihajlovic

Sanja Stankovic

Tanja Jozic

Irena Jozic

Milika R. Asanin

Rajai Ahmad

Gregory Y.H. Lip

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External Validation of the Simple NULL-PLEASE Clinical Score in Predicting Outcome of Out-of-Hospital Cardiac Arrest

BackgroundRapid clinical decision-making on further management of patients with out-of-hospital cardiac arrest may be challenging. Recently, a “futility” score (NULL-PLEASE) incorporating multiple adverse resuscitation features (Nonshockable rhythm, Unwitnessed arrest, Long no-flow or Long low-flow period, blood PH &lt;7.2, Lactate &gt;7.0 mmol/L, End-stage chronic kidney disease on dialysis, Age ≥85 years, Still resuscitation, and Extracardiac cause) has been proposed to help identify patients with out-of-hospital cardiac arrest unlikely to survive; however, external independent score validation is lacking.MethodsWe retrospectively validated the NULL-PLEASE predictive ability for early in-hospital outcome of out-of-hospital cardiac arrest in a single-center cohort of 547 consecutive patients with out-of-hospital cardiac arrest who were admitted from April 2013 to October 2016 (mean age, 66.3 ± 13.2 years); 227 patients (41.5%) died. Because pH and lactate were inconsistently measured, a modified NULL-PLEASE score excluding both variables was calculated as the principal analysis. A sensitivity analysis included the subgroup with pH data available (n = 177).ResultsLong low-flow period and age ≥85 years were independently associated with fatal outcome (both P &lt; .001). Patients with a modified NULL-PLEASE score of ≥5 had a 3.3-fold greater risk of fatal outcome compared with a score of 0 to 4 (odds ratio, 3.34; 95% confidence interval [CI], 2.29-4.89; P &lt; .001); 77% of nonsurvivors had a score ≥5; NULL-PLEASE showed a modest predictive ability for fatal outcome (c-statistic 0.658; 95% CI, 0.613-0.704; P &lt; .001). Sensitivity analysis yielded similar results, with 88% of nonsurvivors having a score ≥5.ConclusionsThe NULL-PLEASE score was predictive for early in-hospital outcome of out-of-hospital cardiac arrest, with a 3.3-fold greater odds for fatal outcome at the score values of ≥5.</p

AV in DH: State of the Field

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