Effects of Vitexin on pulmonary histopathological analysis, lung injury score, lung permeability, and lung water content in lipopolysaccharide (LPS)-treated mice.
- Publication date
- Publisher
Abstract
<p>Representative haematoxylin-eosin staining images of pulmonary section (A): a, control group (wild type (WT) mice treated with sterile phosphate-buffered saline (PBS)+vehicle); b, WT mice treated with PBS+Vitexin; c, nuclear factor erythroid-2-related factor 2 (Nrf2) gene knockout (Nrf2-/-) mice treated with LPS+vehicle; d, WT mice treated with LPS+vehicle; e, WT mice treated with LPS+Vitexin; f, Nrf2-/- mice treated with LPS+Vitexin. All photographs were taken at 100×magnification. Lung injury score (B). Protein concentrations in bronchoalveolar lavage fluid (BALF) (C). Pulmonary wet to dry (W/D) weight ratio (D). Data was expressed as means ± SEM (n = 6–10 per group). * <i>p</i> < 0.05, versus control group; <sup>#</sup><i>p</i> < 0.05, versus LPS+vehicle group; ** <i>p</i> < 0.05, versus LPS+Vitexin treated WT mice.</p
