Spectral analysis of EEG from channel Fz for both dexmedetomidine sedation and propofol sedation.

Abstract

<p>(A-B) Mean power spectra of WA (red), MS (green), DS (blue) and RS (black) for the two agents. (C-D) The green line represents the bootstrapped mean spectra of the difference between MS and WA for the two agents, and the gray space represents the bootstrapped 95% confidence interval bounds for the difference. (E-F) The blue line represents the bootstrapped mean spectra of the difference between DS and WA for the two agents, and the gray space represents the bootstrapped 95% confidence interval bounds for the difference. (G-H) The black line represents the bootstrapped mean spectra of the difference between RS and WA for the two agents, and the gray space represents the bootstrapped 95% confidence interval bounds for the difference. (I-J) The blue line represents the bootstrapped mean spectra of the difference between DS and MS for the two agents, and the gray space represents the bootstrapped 95% confidence interval bounds for the difference. The horizontal solid red lines represent the frequency ranges at which significant differences exist between each sedation state and WA, and the solid green lines represent the frequency ranges at which significant differences exist between DS and MS. WA, wakefulness; MS, moderate sedation; DS, deep sedation; RS, recovery state (RS).</p