Concise
total syntheses of callistrilones A–E have been
achieved from <b>7</b> and commercially available α-phellandrene
(<b>8</b>). The synthetic strategy, which was primarily inspired
by the biogenetic hypothesis, was enabled by an oxidative [3 + 2]
cycloaddition followed by a Michael addition and an intramolecular
nucleophilic addition to construct the target molecules. Moreover,
viminalin I was also synthesized, and its absolute configuration was
unambiguously confirmed
