<p><b>Copyright information:</b></p><p>Taken from "IL-23 induces human osteoclastogenesis via IL-17 , and anti-IL-23 antibody attenuates collagen-induced arthritis in rats"</p><p>http://arthritis-research.com/content/9/5/R96</p><p>Arthritis Research & Therapy 2007;9(5):R96-R96.</p><p>Published online 23 Sep 2007</p><p>PMCID:PMC2212562.</p><p></p> Paw volumes of control rats, vehicle-treated rats with collagen-induced arthritis (CIA), and rats with CIA that were treated with anti-IL-23 antibody, from day 0 to day 21. Open squares, rats with CIA treated with vehicle; open circles, controls; filled triangles, rats with CIA treated with 3.0 μg of anti-IL-23 antibody; filled diamonds, rats with CIA treated with 6.0 μg of anti-IL-23 antibody. Means ± SD are shown. = 0.021 versus controls, = 0.021 versus controls, = 0.014 versus vehicle, = 0.007 versus vehicle (Mann–Whitney test). Arthritis scores of control rats, vehicle-treated rats with CIA, and rats with CIA that were treated with anti-IL-23 antibody, from day 0 to day 28. Open squares, rats with CIA treated with vehicle; open circles, controls; filled triangles, rats with CIA treated with 3.0 μg of anti-IL-23 antibody; filled diamonds, rats with CIA treated with 6.0 μg of anti-IL-23 antibody. Means ± SD are shown. = 0.021 versus controls, = 0.021 versus controls (Mann–Whitney test)
