(–)– plots of perturbed spike-in dataset after SUB-SUB normalization

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Sub-array normalization subject to differentiation"</p><p>Nucleic Acids Research 2005;33(17):5565-5573.</p><p>Published online 4 Oct 2005</p><p>PMCID:PMC1243797.</p><p>© The Author 2005. Published by Oxford University Press. All rights reserved</p> The -axis is the average of log-intensities from two arrays. The -axis is their difference after normalization. In the top four subplots, 20% randomly selected genes have been artificially up-regulated by 2.5-fold in Array Q, R, S and T. The differentiated genes are marked red, and undifferentiated genes are marked black. The trimming fractions in the subplots are: A, 50%; B, 30%; C, 20%; D, 10%. In the two subplots at the bottom, 20% randomly selected genes have been artificially up-regulated by 1.5-fold in Array Q, R, S and T. The trimming fractions are: E, 50%; F, 0%