Comparisons of the copy number of mtDNA and nuclear DNA in various strains

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Adaptive expression responses in the Pol-γ null strain of depleted of mitochondrial genome"</p><p>http://www.biomedcentral.com/1471-2164/8/323</p><p>BMC Genomics 2007;8():323-323.</p><p>Published online 15 Sep 2007</p><p>PMCID:PMC2045682.</p><p></p> The left panel is the plot of fluorescence versus PCR cycle number. The arrows indicate the median of Ct-values for either mtDNA (mt; in green) or nuclear DNA (nc; in purple). The right panel is the box-plot representing the distribution Ct-values by primer pairs either specific to mtDNA (in green) or nuclear DNA (in purple): the minimal (left-end bar), the first quantile (left side of the box), median (central think bar), the third quantile (right side of the box), and the maximal (right-end bar). The copy number of nuclear DNA in various strains is set to 1 as reference for the copy number of mtDNA. The assays were carried out using total DNA samples extracted from wild type (A), (B), (C), and (D) cells as indicated

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