An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model-3

Abstract

<p><b>Copyright information:</b></p><p>Taken from "An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model"</p><p>http://www.biomedcentral.com/1471-213X/7/131</p><p>BMC Developmental Biology 2007;7():131-131.</p><p>Published online 29 Nov 2007</p><p>PMCID:PMC2211317.</p><p></p> tissue types in all tumours, and multiple HSA21 PCR markers were negative in the deleted regions, deletions must have occurred before any differentiation of ES cells in the tumours took place. The regions of the HSA21 gene map which are trisomic in some of the current segmental trisomy mouse models are indicated on the right by vertical lines, for comparison

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