COX-2 protein expression in breast and ovarian cancer cell lines stably transfected with

Abstract

<p><b>Copyright information:</b></p><p>Taken from "Adenovirus type 5 -induced apoptosis in COX-2-overexpressing breast cancer cells"</p><p>http://breast-cancer-research.com/content/9/4/R41</p><p>Breast cancer research : BCR 2007;9(4):R41-R41.</p><p>Published online 5 Jul 2007</p><p>PMCID:PMC2206712.</p><p></p> MDA-MB-231-stable transfectants produced the greatest amounts of COX-2; MDA-MB-435-cells produced 78% of that amount, but the SKOV3.ip1-and MCF-7-cells produced only 6% of that amount. MDA-MB-231-cells expressed slightly more E1A than the other three cell lines. COX-2 protein expression level between the stable transfectants and their corresponding vector control cells or parent cells. If the COX-2 expression levels of each transfectant is defined as 100%, the corresponding COX-2 expression levels of the vector controls were as follows: 65% for MDA-MB-231, 144% for MDA-MB-435, 71% for SKOV3.ip1 and 67% for MCF-7

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