(A) PAE cells stably expressing GFP-Rac1 at levels below endogenous Rac1 (Fig

Abstract

S1, available at ) were scored for the percentage of cells showing strong nuclear fluorescence before and 16 h after the addition of increasing amounts of the indicated compounds. Representative cells at the indicated dose are shown with the percentage of cells showing each phenotype indicated (left), and cumulative dose-response data are shown on the right (mean ± SEM; = 3). Bars, 10 μm. (B) Endogenous Rac1, Ras, and RCC1 were measured in the nuclear fractions as described in before and after the addition of 50 μM apigenin for 24 h (mean ± SEM; = 4).<p><b>Copyright information:</b></p><p>Taken from "Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division"</p><p></p><p>The Journal of Cell Biology 2008;181(3):485-496.</p><p>Published online 5 May 2008</p><p>PMCID:PMC2364699.</p><p></p

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