Proportion of predicted number of transcripts for the simulation performed with 100 genes (synthetic data)

Abstract

The 100 genes used have been randomly selected from the human genome with two to five transcripts. Each of the genes have been simulated 200 times for different noise, concentrations and affinities. The area of each circle represents the proportion of times the corresponding predicted number is chosen by the algorithm for a given number of transcripts. The algorithm tends to underestimate the number of transcripts as the real number of transcripts increases.<p><b>Copyright information:</b></p><p>Taken from "SPACE: an algorithm to predict and quantify alternatively spliced isoforms using microarrays"</p><p>http://genomebiology.com/2008/9/2/R46</p><p>Genome Biology 2008;9(2):R46-R46.</p><p>Published online 29 Feb 2008</p><p>PMCID:PMC2374713.</p><p></p