FRET measurements suggest that mutation of Arg perturbs the interaction of MCT1 with basigin

Abstract

COS cells were cotransfected with MCT1-c-CFP and basigin-c-YFP constructs containing the mutations indicated and live cell imaging with determination of FRET performed as described under ‘Methods’. Data are presented as means±SEM for the number of observations shown.<p><b>Copyright information:</b></p><p>Taken from "The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity"</p><p></p><p>Molecular Membrane Biology 2006;23(6):486-498.</p><p>Published online 13 Dec 2006</p><p>PMCID:PMC2409183.</p><p></p

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