Rs in each experimental group is shown at the end of treatment (L = left side, R = right side). Both As-ODN and ATRA treatment resulted in an inhibition of tumor volume and tumor weight as compared to control group. * < 0.01, one-way ANOVA. In addition, highly significant interactions exist between hTR As-ODN and ATRA. * * F = 10.743, = 0.002, two-way ANOVA. The combination of As-ODN and ATRA resulted in a significant enhancement of the reduction in tumor growth when compared with monotherapy of As-ODN or ATRA alone (< 0.01).<p><b>Copyright information:</b></p><p>Taken from "Antisense oligonucleotides and all-trans retinoic acid have a synergistic anti-tumor effect on oral squamous cell carcinoma"</p><p>http://www.biomedcentral.com/1471-2407/8/159</p><p>BMC Cancer 2008;8():159-159.</p><p>Published online 3 Jun 2008</p><p>PMCID:PMC2427037.</p><p></p
