High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies-2

Abstract

and TX440 in orange). : A p.S768I in TX53, a p.H773_R776insYNPY in TX383 and a p.D770_H773insGSVD in TX440 mutation are detected by sequencing from the HRM positive samples. : The difference plot of HRM exon 21 shows three HRM positive samples (TX23 in red, TX44 in purple and TX324 in orange). : Sequencing chromatograms show a p.R836R SNP in TX23, a p.R836C in TX44 and a p.L858R mutation in TX324.<p><b>Copyright information:</b></p><p>Taken from "High resolution melting analysis for rapid and sensitive and mutation detection in formalin fixed paraffin embedded biopsies"</p><p>http://www.biomedcentral.com/1471-2407/8/142</p><p>BMC Cancer 2008;8():142-142.</p><p>Published online 21 May 2008</p><p>PMCID:PMC2408599.</p><p></p