Cytochalasin A causes MyoE-GFP to disperse from the Spitzenkörper.

Abstract

<p>Images are maximum intensity projections of Z-series stacks. Time (in sec) after the addition of DMSO (top row) or an equivalent volume of cytochalasin A dissolved in DMSO to give a final concentration of 1 µg/ml (bottom row). MyoE-GFP continuously localizes to the Spitzenkörper in the solvent control (top row) but disperses in less than 328 sec after the addition of cytochalasin A.</p