<p>Distributions of unweighted and family-wighted correlation coefficients of CD25<sup>bright</sup>/CD4<sup>+</sup> aTreg frequencies (A) and log-transformed IgG anti-Sm (B) with all 130 single immunoblot reactivities are shown within SLE patients, unaffected relatives and unrelated controls, respectively. Reactivities to cytoplasmic bands are indicated by filled circles, anti-nuclear reactivities by triangles and anti-brain reactivities by crosses. Annoteted P-values were calculated by the described permutation test.</p
