Artemisinin resistance and different elimination strategies.

Abstract

<p>Effect of an increasing prevalence of resistance (defined as the proportion of infections which are artemisinin resistant) from 0% to 80% on the success of MDA with ACT plus multiple rounds of primaquine and treatment with <b>A</b> ACT or <b>B</b> ACT plus single dose primaquine from 2004–2007. <b>C–D</b> effects of different treatment and MDA regimes on the spread of artemisinin resistance (<b>C</b>: prevalence of resistant infections, <b>D</b>: number of resistant infections), presuming a starting prevalence of resistance of 5%. Interventions ceased in 2007.</p