The SPR analysis of the interactions between ClfB and dermokine peptides.

Abstract

<p>A. Panel of dermokine peptides. Peptide 1 corresponds to the 9-residue peptide derived from dermokine protein (253–261). The substituted peptides (Peptides 2–10) have individual amino acids replaced with Ala and peptide 11 is the six amino acid peptide. (B–L). The SPR analysis of the binding between ClfB and Peptides 1–11. Navy, 2000 µM; Magenta, 1000 µM; Dark cyan or dark yellow, 500 µM; Blue, 250 µM; Red, 125 µM; Green, 62.5 µM; Black, 31.25 µM. K_D values of individual binding assays are indicated below the sensorgrams.</p