<p>A: Western blot results using BM cell lysates (n = 3 for each genotype) for detection of GRP78, phospho-eIF2α, total eIF2α, CHOP, ATF6 (p50), ATF6 (p90), calreticulin, pro-caspase-7 intermediate, cleaved caspase-7 and β-actin. B: (Upper panel) RT-PCR results for detection of <i>xbp-1</i> spliced [<i>xbp-1(s)</i>], <i>xbp-1</i> unspliced [<i>xbp-1(u)</i>] and <i>β-actin</i> mRNA levels from BM cells of <i>78<sup>f/f</sup></i> and <i>c78<sup>f/f</sup></i> mice (n = 3 for each genotype). The PCR image was inverted for better clarity. (Lower panel) Quantitation of the ratio of <i>xbp-1(s)</i> to <i>xbp-1(u)</i>. The average ratio of <i>xbp-1(s)</i>/<i>xbp-1(u)</i> in <i>78<sup>f/f</sup></i> was set as 1. The data is presented as mean ± s.e. (*P<0.05, Student’s <i>t</i> test).</p
