OVA-sensitized asthmatic rat models were established successfully.

Abstract

<p>Airway function was detected and BAL fluid and serum were collected and evaluated by ELISA. <b>A</b>, R<sub>L</sub> and Cdyn values were obtained in response to increasing concentrations of inhaled MCh, as described in material and methods. Data represented mean±SEM (n = 20 in each group). *<i>p</i><0.05. <b>B</b>, Cellular composition of BAL fluid. <b>C</b>, Cytokine levels in BAL fluid and serum. <b>D</b>, Eotaxin levels in BAL fluid and serum. IgE levels in serum. Total, total cells; Epi, epithelium; Mac, macrophages; Lym, lymphocytes; Neu, neutrophils; Eos, eosinophils. Date represent the mean±SEM (n = 20 in each group). *<i>p</i><0.05, **<i>p</i><0.01 significant differences comparing asthmatic group and control group.</p

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