Phosphorylation kinetics of Itk, PLCγ1, and PLCγ2 in SLP-76 reconstituted and deficient cells.

Abstract

<p>Phosphorylation kinetics of A) Itk Y512, B) PLCγ1 Y771, and C) PLCγ2 Y753 in the presence (WT) and absence of SLP-76 (ΔSLP76) are represented for 8 timepoints. Results represent the means of three replicate experiments (error bars indicate SD). “*” represents timepoints with significant changes (less than 2% false discovery rate) in phosphorylation abundance between WT and ΔSLP76 cells.</p

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