<p>A) Schematic drawings of the <i>Grp94</i> wild-type (WT) allele, the floxed allele and the knockout (KO) allele. The exons are boxed and numbered. The loxP sites (closed triangle) and the FRT site (open triangle) and expected PCR products for genotyping is indicated. B) Representative BM PCR genotyping results of mice with indicated genotypes after pI.pC injection. C) <i>Grp94</i> mRNA expression measured by quantitative real-time PCR from WT (n = 16) and cKO (n = 18) mouse BM after pI.pC injection. The level of <i>Grp94</i> mRNA was normalized against the level of internal control <i>18S RNA</i>. The data are presented as mean ± s.e., ***p<0.001.</p
