ROCK activity was measured in the presence of either PI3K/Akt inhibitor, LY294002, or JAK2 inhibitor, AG490, by quantifying the phosphorylation level of ERM.

Abstract

<p>Representative bands for p-ERM and total ERM were shown for each group rats (n = 6 for either sham or I/R group rats treated with LY294001 or AG490, the other group rats are the same as shown above). All data expressed as mean±SD. * denotes P<0.05 vs. sham group.</p