Abstract

<p>The bars indicate the number of years of life lost for each category, and the vertical lines are the 95% CIs. The reference category is normal weight and 7.5+ MET-h/wk of physical activity (i.e., meeting US recommended physical activity levels). Normal weight is a BMI of 18.5–24.9 kg/m<sup>2</sup>, overweight is a BMI of 25.0–29.9 kg/m<sup>2</sup>, obese class I is a BMI of 30.0–34.9 kg/m<sup>2</sup>, and obese class II+ is a BMI of 35.0 kg/m<sup>2</sup> or greater. Years of life expectancy lost after age 40 were derived using direct adjusted survival curves <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001335#pmed.1001335-Ghali1" target="_blank">[31]</a>,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001335#pmed.1001335-Makuch1" target="_blank">[32]</a> for participants who were 40+ y of age at baseline and not underweight (96.5% of participants). Life expectancy models used age as the underlying time scale and were adjusted for gender, alcohol consumption (0, 0.1–14.9, 15.0–29.9, 30.0+ g/d), education (did not complete high school, completed high school, post-high-school training, some college, completed college), marital status (married, divorced, widowed, unmarried), history of heart disease, history of cancer, and smoking status (never, former, current).</p

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