Virus-mediated induction of intracellular defense factors can lead to peaks in <i>R<sub>0</sub></i> for two different viral strategies, <i>s</i>: a “stealth strategy” and a “saturation strategy”.

Abstract

<p>Plotted is the basic reproductive ratio, <i>R<sub>0</sub></i>, as a function of strategy, <i>s</i>, for two different values of the infectivity parameter, <i>r<sub>2</sub></i>. The rest of the parameters are as follows: , <i>d = 0.1</i>, <i>a = 4</i>, <i>n<sub>1</sub> = 16</i>. The infectivity parameter <i>r</i> depends on the strategy. It is given by <i>r = r<sub>2</sub>-s(r<sub>2</sub>-r<sub>2</sub>/10)/10</i> if <i>s<10</i>, and <i>r = r<sub>2</sub>/10</i> if . These functions are shown in the inset for the two values of <i>r<sub>2</sub></i>.</p

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